Maroua Moslah, K. Djebbi, C. Tlili, C. Dridi, Deqiang Wang
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引用次数: 0
Abstract
Herein, we develop a fluorescent sensor for simple detection of miRNA-10b, which combines the fluorescence quenching ability of graphene oxide (GO) and the duplex-specific nuclease (DSN) mediated target recycling amplification. Our sensor exhibits desirable sensitivity for miRNA-10b with a 530 fM detection limit that could be achieved within 75 min. Furthermore, our sensor showed good selectivity for discriminating target miRNA and other microRNAs.