N. Agafonova, E. Shchegolkov, Y. Burgart, V. I. Saloutin, M. Ulitko
{"title":"Synthesis of biological active compounds based on trifluoromethylcontaining 4-nitrosopyrazoles","authors":"N. Agafonova, E. Shchegolkov, Y. Burgart, V. I. Saloutin, M. Ulitko","doi":"10.32460/ISHMU-2020-8-0009","DOIUrl":null,"url":null,"abstract":"e-pot nitrosation of 1,3-diketones or their lithium salts followed by treatment of hydrazines. Reduction of the nitroso-derivatives made it possible to obtain the 4-amino-3-trifluoromethylpyrazoles chlorides. Cytotoxic activity of the compounds wase evaluated in vitro","PeriodicalId":154439,"journal":{"name":"VIII Information school of a young scientist Central Scientific Library of the Urals Branch of the Russian Academy of Science","volume":"42 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"VIII Information school of a young scientist Central Scientific Library of the Urals Branch of the Russian Academy of Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32460/ISHMU-2020-8-0009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
e-pot nitrosation of 1,3-diketones or their lithium salts followed by treatment of hydrazines. Reduction of the nitroso-derivatives made it possible to obtain the 4-amino-3-trifluoromethylpyrazoles chlorides. Cytotoxic activity of the compounds wase evaluated in vitro
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