Screen-printed amperometric biosensors: A balancing act of manufacturing properties, cost efficiency and sensitivity

E. Melnik, Vanessa Thöny, S. Kurzhals, G. Mutinati, Malahat Asadi, Pooyan Mehrabi, T. Schalkhammer, R. Hainberger
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引用次数: 1

Abstract

Amperometric sensors can be used for many applications, as they can be excellently manufactured in roll-to-roll printing processes. However, careful material selection is of particular importance for high sensitivity and selectivity. For example, the choice of the reference electrode material is critical to ensure a stable electrical potential, and the working electrode material needs to match the redox system used. For biosensor applications, the immobilization of the receptor molecules via printing technologies must be ensured, for which again the sensor materials significantly contribute. To illustrate these challenges, examples are presented for the detection of small molecules, proteins and DNA.
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丝网印刷安培生物传感器:制造性能,成本效率和灵敏度的平衡行为
安培传感器可以用于许多应用,因为它们可以在卷对卷印刷过程中出色地制造。然而,对于高灵敏度和选择性,谨慎的材料选择尤为重要。例如,参考电极材料的选择对于确保稳定的电位至关重要,工作电极材料需要与所使用的氧化还原系统相匹配。对于生物传感器的应用,必须确保通过打印技术固定受体分子,为此传感器材料也做出了重大贡献。为了说明这些挑战,给出了小分子、蛋白质和DNA检测的例子。
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