Effect of the Aqueous Stem Bark Extract of Schumanniophyton magnificum on Reproductive Functions on Wistar Strain Mature Female Rats

Abstract

In recent years, the rate of infertility has not stopped increasing in the world. The aim of the present study was to evaluate the effects of the aqueous extract of Schumanniophyton magnificum (Rubiaceae) on cyclicity, ovulation and gestation in mature rats. Methods: After a qualitative phytochemical analysis of these aqueous extracts, the experimental studies carried out were based on the evaluation of the pro-fertility effects of this extract in mature rats. For this purpose, 35 rats were used for the estrous cyclicity test and treated for 21 days at the end of which vaginal smears were taken and the duration, as well as the frequency of the appearance of the phases of the cycle, were evaluated. The ovulation test was performed on 80 female rats, which were divided into two groups of 40 animals and treated respectively in the morning and evenin g with distilled water, β-oestradiol or plant extract at doses of 200, 400 and 800 mg/kg. treatment of certain cases of female infertility in Cameroon.