Study of the Relationship of Lipid Profile, BMI and Blood Pressure among Non-diabetic Hypertensive Patients - A Hospital Based Study

Dristi Baskota, Bishow Raj Shrestha, S. Tiwari, Pragati Poudyel, Rachana Pandey, Richa Joshi
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Abstract

Introduction: Several research have demonstrated the connection between lipid levels, diabetes mellitus (DM), and hypertension, but none have focused specifically on the association between lipid levels and essential hypertension in Nepal's non-diabetic population. Aims: To study the relationship between lipid profile, body mass index (BMI), and blood pressure (BP) in the nondiabetic hypertensive population. Methods: A hospital-based cross-sectional study was conducted among 150 participants. Anthropometric measurements including height, weight and BP were taken. Blood was collected in serum vial for lipid profile [total cholesterol (TC), triglyceride (TG) and low and high density lipoprotein cholesterol (LDLC and HDLC)] after an overnight fasting. Results: 44.7% were female, and 55.3% were male with the age ranging between 28-80 years. Among 48.67% of the overweight participants, 56.8% were male. 25.33% were obese, among which 52.6% were male. 56% of participants had systolic blood pressure (SBP) ≥140 mmHg and 58% had diastolic blood pressure (DBP) ≥90 mmHg and showed no significance among the gender. Borderline TG level was observed in 76.2% of participants with SBP ≥140 mmHg and in 74.7% with DBP ≥90 mmHg. HDLC vs gender showed significance. SBP and DBP had a significant relationship with LDLC and TC. The association of BMI with BP and lipid profile was not significant. Conclusion: Dyslipidemia is prevalent among non-diabetic hypertensive individuals. The majority of participants were overweight, however blood pressure and lipid profile did not correlate with BMI presumably because other anthropometric characteristics have better predictive values than BMI.
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非糖尿病性高血压患者血脂、BMI与血压关系的医院研究
一些研究已经证明了脂质水平、糖尿病(DM)和高血压之间的联系,但没有一个研究专门关注尼泊尔非糖尿病人群中脂质水平和原发性高血压之间的关系。目的:研究非糖尿病性高血压人群血脂、体重指数(BMI)和血压(BP)之间的关系。方法:对150名参与者进行了以医院为基础的横断面研究。测量身高、体重和血压。禁食一夜后,取血清瓶进行血脂分析[总胆固醇(TC)、甘油三酯(TG)、低、高密度脂蛋白胆固醇(LDLC和HDLC)]。结果:女性44.7%,男性55.3%,年龄28 ~ 80岁。在48.67%的超重参与者中,56.8%是男性。肥胖占25.33%,其中男性占52.6%。56%的参与者收缩压(SBP)≥140 mmHg, 58%的参与者舒张压(DBP)≥90 mmHg,性别差异无统计学意义。收缩压≥140 mmHg的76.2%的参与者和舒张压≥90 mmHg的74.7%的参与者观察到临界TG水平。HDLC与性别有显著性差异。收缩压、舒张压与LDLC、TC有显著相关。BMI与血压和血脂的相关性不显著。结论:血脂异常在非糖尿病性高血压人群中普遍存在。大多数参与者都超重,但血压和血脂与BMI无关,这可能是因为其他人体测量特征比BMI具有更好的预测价值。
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