Effect Of Ethanol Extract Jackfruit (Artocarpus Heterophyllus Lam.) To Decrease Blood Sugar Levels In Wistar Female White Rats With Streptozotocin-Induced Gestational Mellitus Diabetes

Abstract

Background: Hormonal and metabolic changes during pregnancy cause the pregnancy to be diabetogenic, in which GDM tends to become heavier during pregnancy and will facilitate the occurrence of various complications. DMG mothers approximately 1.7% can cause perinatal mortality, 4.3% give birth to children by surgery, 7.3% give birth to children whose birth weight is more than 4.5 kg and 23.5% can cause cases of dystocia. shoulder during labor. Methods: The study was conducted using a literature review method that focuses on the results of writing related to the effects of the Jackfruit Seed (Artocarpus heterophyllus Lam.) ethanol extract on female Wistar rats with gestational diabetes mellitus induced by Streptozotocin by browsing accredited journal sites such as Google Schoolar, Google, and Pubmed, in the period 2016-2021. Conclusion: Based on the research conducted, there was an effect of giving ethanol extract of jackfruit seeds (Artocarpus heterophyllus Lam.) to decrease blood sugar levels in female wistar rats with gestational diabetes mellitus induced by streptozotocin