RNAs and extracellular vesicles - Keeping up the appearances

Marie-Luise Mosbach, E. Pogge von Strandmann, C. Preußer
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Abstract

Since the advent of extracellular vesicle (EV) research in the last decade, these particles have been associated with RNAs. Traded as promising new biomarkers, RNA transport vehicles, or ultimately as potential therapeutic RNA delivery vehicles. However, this view is currently undergoing a change in which RNA may no longer be a major component of EVs. In this short opinion paper, we would like to encourage a reconsideration of our view on EVs and RNAs and open it up to new thoughts.
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rna和细胞外囊泡-保持表象
自近十年来细胞外囊泡(EV)研究出现以来,这些颗粒已与rna相关联。作为有前途的新生物标志物,RNA运输载体,或最终作为潜在的治疗性RNA递送载体进行交易。然而,这种观点目前正在发生变化,RNA可能不再是电动汽车的主要组成部分。在这篇简短的意见论文中,我们希望鼓励人们重新考虑我们对电动汽车和rna的看法,并提出新的想法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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RNAs and extracellular vesicles - Keeping up the appearances The more the better – determining the optimal range when performing single-vesicle phenotyping Establishment of a DFG-funded research group on the topic of plant-microbe communication through extracellular RNA Extracellular vesicle therapeutics: the issue of one size fits all
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