Central nervous system Tuberculomas in a patient with disseminated multi-drug resistant tuberculosis; A case report

International Journal of Current Research in Medical Sciences Pub Date : 2021-01-30 DOI:10.22192/ijcrms.2021.07.01.001

H. Kaur, Dilbagh Singh, A. Kaur, N. Kajal, Mukul Sharma

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Abstract

Tuberculosis (TB) is one of the leading causes of death worldwide, particularly in low- and middle-income countries. Although Mycobacterium tuberculosis can involve any organ, most commonly the lung, central nervous system (CNS) tuberculosis is the most devastating form of the disease. Tuberculoma is the most common parenchymal lesion in CNS tuberculosis which could be found in any portion of the intracranial space. The global rates and numbers of drug resistant TB are rising. With increasing globalization, the spread of drug-resistant strains of TB has become a mounting global public health concern. We present a case of 27-year-old male with disseminated multi-drug resistant (MDR) TB who presented with neurological symptoms and multiple CNS Tuberculomas. The patient was started on regimen for Multi-drug resistant tuberculosis (MDR-TB), which allowed the serial resolution of intracranial tuberculomas. Keywords: Tuberculosis (TB), Multi-drug resistant (MDR) TB, Central nervous system (CNS) TB, Tuberculoma, MRI brain

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播散性耐多药结核病患者的中枢神经系统结核瘤病例报告

结核病是世界范围内的主要死亡原因之一，特别是在低收入和中等收入国家。虽然结核分枝杆菌可累及任何器官，最常见的是肺，但中枢神经系统(CNS)结核是该疾病最具破坏性的形式。结核瘤是中枢神经系统结核中最常见的实质病变，可在颅内间隙的任何部位发现。全球耐药结核病的发病率和数量正在上升。随着全球化程度的提高，耐药结核菌株的传播已成为一个日益严重的全球公共卫生问题。我们报告一例27岁男性弥漫性耐多药(MDR)结核病患者，其表现为神经系统症状和多发性中枢神经系统结核瘤。患者开始接受耐多药结核病(MDR-TB)治疗方案，该方案允许颅内结核瘤的连续解决。关键词:结核，耐多药结核，中枢神经系统结核，结核瘤，MRI脑

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International Journal of Current Research in Medical Sciences

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