Lohit kumar Kalita, C. Kalita, P. Gogoi, U. Sharma
{"title":"A Rare Case Report of Acute T-cell Lymphoblastic Leukaemia Presenting with Cutaneous Involvement in a Child","authors":"Lohit kumar Kalita, C. Kalita, P. Gogoi, U. Sharma","doi":"10.9734/bpi/nfmmr/v1/10757d","DOIUrl":null,"url":null,"abstract":"Primary cutaneous involvement in T-cell lymphoblastic leukemia is rare in childhood. We present a case of 6-year- old girl admitted to our hospital because of multiple skin lesions. She was looked pale and weak. Generalized lymphadenopathy was present. Complete blood count revealed 216,000/mm3 white blood cell count. Peripheral blood smear showed 80% lymphoblasts. Bone marrow aspiration revealed 96% blastic cells with immunophenotype and morphological characteristics of acute lymphoblastic leukemia (T-ALL) which was confirmed by flowcytometry. ALL BFM -95 remission induction treatment protocol was started. Skin lesion remained same after two month of the cytotoxic therapy. The symptoms became more aggressive and she died after 4 months of treatment.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"37 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"New Frontiers in Medicine and Medical Research Vol. 1","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9734/bpi/nfmmr/v1/10757d","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Primary cutaneous involvement in T-cell lymphoblastic leukemia is rare in childhood. We present a case of 6-year- old girl admitted to our hospital because of multiple skin lesions. She was looked pale and weak. Generalized lymphadenopathy was present. Complete blood count revealed 216,000/mm3 white blood cell count. Peripheral blood smear showed 80% lymphoblasts. Bone marrow aspiration revealed 96% blastic cells with immunophenotype and morphological characteristics of acute lymphoblastic leukemia (T-ALL) which was confirmed by flowcytometry. ALL BFM -95 remission induction treatment protocol was started. Skin lesion remained same after two month of the cytotoxic therapy. The symptoms became more aggressive and she died after 4 months of treatment.
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