Diabetes Mellitus Tipe 2 sebagai Faktor Predisposisi dan Komorbid Tuberkulosis Multi Drug Resisten Primer

Abstract

Multi Drug Resistant Tuberculosis (MDR-TB) was a health problem in worldwide. Indonesia was one of the 27 countries with a high burden of MDR TB in the world, an estimated 6800 DIABETES MELLITUS TIPE 2 SEBAGAI FAKTOR PREDISPOSISI DAN KOMORBID TUBERKULOSIS MULTI DRUG RESISTEN PRIMER 42 new cases per year, 2.8% were new cases and 16% have received anti TB drugs before. Primary MDR TB occured in patient who have never received anti TB drugs treatment. Diabetes mellitus was a predisposing and comorbid factor that could accelerate TB disease and complicate treatment. We reported primary MDR TB case in patient with type 2 diabetes. Case of male 58 years old with a history of productive cough with yellowish phlegm since 2 months, night sweats and loss of weight and appetite. Rapid molecular test resulted MTB detected medium and rifampicin resistant detected. Chest X-ray showed infiltrate and cavity at the apex of the lung. Patients with type 2 diabetes mellitus have not been controlled for 12 years with HbA1c 10.5%. We concluded that DM is one of predisposing and comorbid factors of primary MDR TB. DM patients were necessary to do TB screening and TB patients also need to be screened for DM. MDR TB treatment in DM patient complied with the national standard MDR TB treatment and blood sugar levels remain under control.