Advantages of tangential excision with simultaneous autodermoplasty for treating burn wounds

T. I. Farmaha, O. Lukavetskyi, O. Chemerys
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Abstract

Burn trauma remains an important health problem, among which thermal burns of the limbs are one of the most common and complex due to the need to restore limb function and reduce aesthetic defects. Early tangential excision with simultaneous autodermoplasty is a complex technique that is also a significant stress for the patient, but it allows achieving all the set goals. Purpose - to evaluate the effectiveness of tangential excision with simultaneous autodermoplasty for treating burn wounds compared to the classical method of treatment. Materials and methods. The study included 24 patients with burns of the upper and/or lower limbs, from which two groups were formed: an experimental group (12 patients) and a control group (12 patients) who were equal in terms of patient sex, age, etiology of burn wounds, affected area. Tangential excision with simultaneous autodermoplasty was applied to patients in the experimental group, while delayed sequential necrectomy, xenoplasty (if necessary), and delayed autodermoplasty were performed on patients in the control group. Results. Patients in the experimental group stayed in the hospital for an average of 10.5±4.5 days, which was almost half as long as in the control group (20.2±3.5 days). The number of surgical interventions in the experimental group was 1.3±0.5 operations, while in the control group it was 2.7±0.8 operations, and the number of general anesthesia procedures in the experimental group was significantly lower (1.3±0.5) than in the control group (4.6±1.1; p<0.05). In the experimental group, the number of dressings for each injury was 4.3±1.6, while in the control group it was almost three times as many (12.7±3.0; p<0.05). The duration of healing of burn wounds in the experimental group was 13.3±4.3 days, which was shorter than in the control group (24.2±3.9 days; p<0.05). The prevalence rate of infectious complications in the experimental group was 21.1% (4 cases), while in the control group it was significantly higher (58.8%). However, the prevalence rate of other complications, such as lysis of skin grafts, was only slightly lower in the experimental group (15.8%, or 3 cases) compared to the control group (29.4%, or 5 cases). 2 (18.2%) burn wounds in the experimental group required secondary reconstruction, while in the control group, 7 (70.0%) wounds required it. Conclusions. Treatment of burn wounds of the upper and/or lower limbs using the method of tangential excision with simultaneous autodermoplasty allows for a reduction in the length of hospital stay, a decrease in the number of surgical interventions, general anesthesia procedures, dressing changes, and ensures faster wound healing, as well as reduces the frequency of complications and the need for secondary reconstruction. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of all participating institutions. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.
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切线切除同时自体皮肤成形术治疗烧伤创面的优点
烧伤创伤仍然是一个重要的健康问题,其中肢体热烧伤是最常见和最复杂的烧伤之一,因为需要恢复肢体功能和减少美学缺陷。早期切向切除同时自体真皮成形术是一项复杂的技术,对患者来说也是一个重大的压力,但它可以实现所有设定的目标。目的:评价切向切除同时自体皮肤成形术治疗烧伤创面的效果,并与传统治疗方法进行比较。材料和方法。本研究纳入24例上肢和(或)下肢烧伤患者,分为实验组(12例)和对照组(12例)两组,两组患者性别、年龄、烧伤创面病因、患处面积等均相同。实验组患者行切向切除同时自体皮肤成形术,对照组患者行延迟顺序切除、异种成形术(如有必要)和延迟自体皮肤成形术。结果。实验组患者平均住院时间为10.5±4.5天,几乎是对照组(20.2±3.5天)的一半。实验组手术干预次数为1.3±0.5次,对照组为2.7±0.8次,全麻手术次数(1.3±0.5次)明显低于对照组(4.6±1.1次);p < 0.05)。实验组每次损伤敷料次数为4.3±1.6次,而对照组几乎是对照组的3倍(12.7±3.0次;p < 0.05)。试验组烧伤创面愈合时间为13.3±4.3 d,明显短于对照组(24.2±3.9 d);p < 0.05)。实验组感染并发症发生率为21.1%(4例),对照组感染并发症发生率为58.8%,明显高于对照组。然而,其他并发症的患病率,如植皮溶解,实验组(15.8%,或3例)仅略低于对照组(29.4%,或5例)。实验组2例(18.2%)创面需要二次重建,对照组7例(70.0%)创面需要二次重建。结论。采用切向切除同时自体皮肤成形术治疗上肢和/或下肢烧伤创面,可缩短住院时间,减少手术干预次数、全身麻醉程序、换药次数,并确保伤口更快愈合,同时减少并发症的发生频率和二次重建的需要。这项研究是按照《赫尔辛基宣言》的原则进行的。研究方案经所有参与机构的当地伦理委员会批准。获得患者的知情同意进行研究。作者未声明存在利益冲突。
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