Multiple Cutaneous Features Associated with Primary Sjogren’s Syndrome

Rosales Sotomayor A, Castro- Molina SA, Mendez Flores Silvia, Barrera Godinez A, Carrillo Cordova Dulce Maria, López-Loya Dominguez Cherit Judith
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Abstract

Sjogren’s syndrome is a systemic autoimmune disorder that mainly affects exocrine glands, although the clinical manifestations include both exocrine gland involvement and extraglandular disease features. In addition to dryness, musculoskeletal pain and fatigue are the hallmarks of this disease and constitute the classic symptom triad presented by the vast majority of patients. The authors present the case of a 59-year-old woman with achalasia, sicca syndrome, subcutaneous nodules affecting the knees, purpuric plaques on the palms and vitiligo. Serological tests were consistent with Sjögren′s syndrome, therefore the diagnosis of primary Sjögren’s syndrome with extensive cutaneous manifestations as extraglandular organ involvement was made.
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原发性干燥综合征相关的多种皮肤特征
干燥综合征是一种主要影响外分泌腺的全身性自身免疫性疾病,其临床表现包括外分泌腺受累和腺外病变特征。除干燥外,肌肉骨骼疼痛和疲劳是本病的标志,构成了绝大多数患者的经典症状三联征。作者提出的情况下,一个59岁的妇女贲门失弛缓症,干燥综合征,皮下结节影响膝盖,紫癜斑在手掌和白癜风。血清学检查与Sjögren综合征一致,因此诊断原发性Sjögren综合征伴有广泛的皮肤表现,如腺外器官受累。
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