Determination of the antifungal activity of Dorema ammonium extract

Abstract

The current investigation included estimating the efficiency of aqueous and ethanolic plant extracts of Dorema ammoniacum plant in inhibiting the growth of fungi, where the ethanolic extract recorded a higher rate of inhibition than the aqueous extract. It is more effective when the concentration is increased in inhibiting the growth of two types of Candida, C. albicans and C. krusei. The aqueous extracts of Dorema ammoniacum had no toxic effect on human red blood cells at concentrations (100, 200, 300) mg/ml at an incubation period of 3 hours. As a result of the widespread use of medicinal plants as antimicrobial drugs, the absence of toxicity on the host cells is considered essential because it is an inexpensive, easy-to-apply, quick-results method and is safe when used as a drug. Keywords: Dorema ammoniacum, D. Don, cytotoxicity activity, Antimicrobial activity.