Role of Collagen in Management of Chronic Non-Healing Wounds

Abstract

Background: A chronic wound does not heal in an orderly set of stages. The healing in such a wound is unpredictable in relation to time contrary to the way most wounds heal. The type of wounds that do not heal within three months are often and should be considered chronic wounds. Aim: To study the efficacy of topical use of collagen granules in wound healing. Material and method: In this prospective study one hundred cases with chronic non-healing wounds were selected and treated with collagen granules topically. The effect on the chronic wounds was studied for three months. The collagen granules were made from 100 % bovine collagen. Observation and result: all the wounds were observed for three months in terms of disappearance of slough, appearance of healthy granulation tissue and complete or incomplete healing. Conclusion: The use of collagen granules dressing accelerated the wound healing in chronic wounds/ulcers. In our study we found that the rate of wound healing was significantly better in using collagen granules.