Study of Stripping of Membranes at Term Gestation to Reduce Post-Term Pregnancies

N. Kulkarni, Richa V Patel
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Abstract

Introduction: Any pregnancy which has passed beyond the expected date of delivery is called a prolonged pregnancy & which have passed 42 weeks, 294 days is called postmaturity or post term pregnany [1], these are at an increased risk for fetal postmaturity syndrome, macrosomia, fetal intolerance of labor, oligohydramnios, meconium-stained amniotic fluid, and cesarean delivery [2]. The clinical evidence of an increased potential for these poor perinatal outcomes has triggered a movement toward increased antenatal testing between 37- 42 weeks of gestation, and cervical ripening with labor inductions at or before 42 weeks of gestation. While a ripe cervix is usually suggestive of fetal maturity to find an unripe cervix does not exclude maturity. Induction of labor is one of the most common procedures in obstetrics and is carried out in approximately 20% of pregnancies [3]. Mechanical and biochemical means have been used to affect cervical ripening and to induce labor. Methods of induction include amniotomy, membrane stripping or sweeping, prostaglandins, laminaria and oxytocin. Membrane stripping or sweeping is a commonly use procedure aimed at preventing the post term pregnancy and avoid the application of formal method of induction of labour. Aims and Objectives: 1. to determine the effectiveness & safety of membrane stripping at term pregnancy as a OPD procedure weekly which can reduce the incidence of Post term pregnancy, labour induction and its complication. 2. To determine what factors occurring after digital separation of the chorionic membranes from the lower uterine segment (membrane stripping) are involved in observed clinical changes compared with patients not so treated. Material and Methods: Study Design: This was a prospective study conducted at department of Obstetrics and Gynaecology at our hospital. Study Duration: Study was conducted during the period of duration September 2014 to September 2016. Results: After documenting the confirm gestational dating criteria and obtaining inform consent 200 patients at 37 complete week of gestation were randomly selected for the study. Data were collected from findings at 1,2,3 week and during labour, which is compaired by pearson chi-square and fischer exact test. Conclusion: Stripping of membranes is a very old procedure. This causes the release of plasma prostaglandin F2, Increase in endocervical phospholipase A activity and oxytocin release have also been observed. This will initiate uterine contraction and onset of labour. It is safe, cheap, effective and even an out patient procedure. It is associated with earlier delivery and decreased incidence of posterm gestation and hence maternal and fetal complication related to post maturity.
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足月剥膜减少足月后妊娠的研究
导语:任何超过预产期的妊娠称为延长妊娠,超过42周、294天的妊娠称为晚期妊娠或足月妊娠[1],这些妊娠发生胎儿晚期综合征、巨大儿、胎儿劳动不耐受、羊水过少、羊粪染色和剖宫产的风险增加[2]。临床证据表明,这些不良围产期结局的可能性增加,这引发了在妊娠37- 42周期间增加产前检查的运动,以及在妊娠42周或之前引产的宫颈成熟。虽然成熟的子宫颈通常暗示胎儿成熟,但发现未成熟的子宫颈并不排除成熟。引产是产科最常见的手术之一,约20%的妊娠会引产[3]。机械和生化手段已被用来影响宫颈成熟和引产。诱导方法包括羊膜切开、剥膜或扫膜、前列腺素、海绵体和催产素。膜剥离或清扫是一种常用的程序,目的是防止后期妊娠和避免应用正式的引产方法。宗旨和目标:确定膜剥离术在足月妊娠期作为OPD程序的有效性和安全性,以减少足月妊娠、引产及其并发症的发生率。2. 目的:确定与未接受手术的患者相比,子宫下段毛膜分离(膜剥离)后观察到的临床变化与哪些因素有关。材料与方法:研究设计:这是一项在我院妇产科进行的前瞻性研究。研究时间:研究时间为2014年9月至2016年9月。结果:在记录确认的妊娠日期标准并获得知情同意后,随机选择200名妊娠37周的患者进行研究。数据收集于1、2、3周和分娩期间的结果,并通过皮尔逊卡方和费舍尔精确检验进行比较。结论:剥膜术是一种非常古老的手术。这导致血浆前列腺素F2的释放,也观察到颈内磷脂酶A活性和催产素释放的增加。这将引起子宫收缩和分娩的开始。它安全、便宜、有效,甚至可以作为门诊手术。它与早期分娩和降低后妊娠发生率有关,因此与后成熟相关的母胎并发症有关。
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