Investigations on instantaneous frequency variations of RR time series in intrinsic mode functions of congestive heart failure subjects

P. Gupta, K. K. Sharma, S. Joshi, A. Dube
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Abstract

The congestive heart failure is a major cause of concern among all types of cardiovascular problems and is attributed to imbalances in sympathetic and parasympathetic nervous systems. In this paper we propose an algorithm for detection of congestive heart failure condition using the variability of instantaneous frequency of intrinsic mode functions obtained using Hilbert-Hunag Transform of RR time series in different subjects. It is observed that the instantaneous frequency of intrinsic mode functions is a key feature that is altered quite significantly with imbalances in autonomic nervous system. It is also observed through simulation results using MATLAB that higher order intrinsic mode functions of RR time series exhibit lower variations of the instantaneous frequency compared to lower order intrinsic mode functions. On the basis of this variability of instantaneous frequency of higher order intrinsic mode functions we are able to detect congestive heart failure condition in different subjects.
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充血性心力衰竭受试者内禀模态函数RR时间序列瞬时频率变化的研究
充血性心力衰竭是所有心血管疾病中引起关注的主要原因,其原因是交感和副交感神经系统失衡。本文提出了一种利用不同受试者RR时间序列的Hilbert-Hunag变换得到的本征模态函数的瞬时频率变异性来检测充血性心力衰竭的算法。我们观察到,固有模态函数的瞬时频率是自主神经系统失衡时显著改变的关键特征。通过MATLAB仿真结果也观察到,RR时间序列的高阶内模态函数比低阶内模态函数的瞬时频率变化更小。基于这种高阶本征模态函数瞬时频率的变异性,我们能够检测不同受试者的充血性心力衰竭状况。
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