Akut Pankreatitte Yeni Bir İnflamatuar Belirteç Olarak Ortalama Trombosit Hacmi ve C-Reaktif Protein ile Başvuru Anındaki Ranson Skoru ile İlişkisi

Abstract

Aim: The study’s aim is to evaluate mean platelet volume (MPV) as a marker of inflammation in patients with acute pancreatitis (AP) and to analyse the relationships among MPV, CRP (C-reactive protein) and Ranson’s score. Material and Methods: In this study, 119 patients with AP (mean age 53.8 ± 18.0 years) and 88 healthy control group (mean age 53.1 ± 6.8 years) were enrolled. Among the patients with AP, 75 were classified as having biliary AP, and 44 were classified as having nonbiliary AP. All patients’ demographic data, clinical and laboratory findings and Ranson’s scores were examined from the hospital’s database. Results: MPV was significantly lower among patients with AP than among the control group (p = 0.001). CRP was significantly higher among patients with AP than among the control group (p< 0.001). The difference in MPV between the biliary and nonbiliary AP group was statistically not significant. When we compared MPV based on patients’ lengths of hospital stay, there was no significant difference. In correlation analysis, there was no correlation among CRP, Ranson’s score and serum MPV levels. Conclusion: We observed that MPV levels in the AP group were lower than healthy controls. Thus, like other inflammation markers, MPV might be a useful marker for AP diagnosis.