A Case of Primary Malignant Melanoma of Ovary

Swati Sudhakar Ghunage, M. Pawar, P. Bagade
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Abstract

Primary ovarian melanoma is considered arising from mature cystic teratoma which is extremely rare condition. As best of our knowledge till date only 49 cases has been reported worldwide. Most cases are associated with disseminated diseases and poor prognosis. We present here a case of a 45 yr lady in perimenopausalage group, came with c/o heavy menstrual bleeding since 1 month and irregular menses since 1 year. The cofirm diagnosis was made on the basis immunohistochemistry. Primary ovarian malignant melanoma is a definite entity and is associated with poor prognosis. Differential diagnosis is difficult for pathologist as it has to be differentiated from metastatic disease. The mainstay treatment of this disease is complete surgical debulking, however chemotherapy and immunotherapy has some role but patient outcome is unpredictable.
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卵巢原发性恶性黑色素瘤1例
原发性卵巢黑色素瘤被认为是由成熟的囊性畸胎瘤引起的,这是一种极其罕见的疾病。据我们所知,迄今为止全球仅报告了49例病例。多数病例伴有播散性疾病和预后不良。我们在此报告一例45岁的围绝经期女性,自1个月以来出现c/o大量月经出血,1年来月经不规律。经免疫组织化学确诊。原发性卵巢恶性黑色素瘤是一种明确的实体,与预后不良有关。鉴别诊断对病理学家来说是困难的,因为它必须与转移性疾病区分开来。本病的主要治疗方法是完全手术切除,但化疗和免疫治疗也有一定作用,但患者的预后难以预测。
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