{"title":"A Case of Primary Malignant Melanoma of Ovary","authors":"Swati Sudhakar Ghunage, M. Pawar, P. Bagade","doi":"10.15713/ins.mmj.42","DOIUrl":null,"url":null,"abstract":"Primary ovarian melanoma is considered arising from mature cystic teratoma which is extremely rare condition. As best of our knowledge till date only 49 cases has been reported worldwide. Most cases are associated with disseminated diseases and poor prognosis. We present here a case of a 45 yr lady in perimenopausalage group, came with c/o heavy menstrual bleeding since 1 month and irregular menses since 1 year. The cofirm diagnosis was made on the basis immunohistochemistry. Primary ovarian malignant melanoma is a definite entity and is associated with poor prognosis. Differential diagnosis is difficult for pathologist as it has to be differentiated from metastatic disease. The mainstay treatment of this disease is complete surgical debulking, however chemotherapy and immunotherapy has some role but patient outcome is unpredictable.","PeriodicalId":448362,"journal":{"name":"MMJ-A Journal by MIMER Medical College, Pune, India","volume":"59 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"MMJ-A Journal by MIMER Medical College, Pune, India","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15713/ins.mmj.42","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Primary ovarian melanoma is considered arising from mature cystic teratoma which is extremely rare condition. As best of our knowledge till date only 49 cases has been reported worldwide. Most cases are associated with disseminated diseases and poor prognosis. We present here a case of a 45 yr lady in perimenopausalage group, came with c/o heavy menstrual bleeding since 1 month and irregular menses since 1 year. The cofirm diagnosis was made on the basis immunohistochemistry. Primary ovarian malignant melanoma is a definite entity and is associated with poor prognosis. Differential diagnosis is difficult for pathologist as it has to be differentiated from metastatic disease. The mainstay treatment of this disease is complete surgical debulking, however chemotherapy and immunotherapy has some role but patient outcome is unpredictable.