A. Candiani, M. Sozzi, E. Coscelli, F. Poli, A. Cucinotta, S. Selleri, R. Veneziano, R. Corradini, R. Marchelli, P. Childs, S. Pissadakis
{"title":"Double Tilted Fiber Bragg Grating for label-free DNA detection","authors":"A. Candiani, M. Sozzi, E. Coscelli, F. Poli, A. Cucinotta, S. Selleri, R. Veneziano, R. Corradini, R. Marchelli, P. Childs, S. Pissadakis","doi":"10.1109/IWBP.2011.5954849","DOIUrl":null,"url":null,"abstract":"We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results are reported, showing that a 10nM DNA solution induces a 10% modulation of the corresponding fringes visibility.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"203 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2011 International Workshop on Biophotonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IWBP.2011.5954849","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results are reported, showing that a 10nM DNA solution induces a 10% modulation of the corresponding fringes visibility.