Double Tilted Fiber Bragg Grating for label-free DNA detection

A. Candiani, M. Sozzi, E. Coscelli, F. Poli, A. Cucinotta, S. Selleri, R. Veneziano, R. Corradini, R. Marchelli, P. Childs, S. Pissadakis
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引用次数: 2

Abstract

We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results are reported, showing that a 10nM DNA solution induces a 10% modulation of the corresponding fringes visibility.
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用于无标签DNA检测的双倾斜光纤光栅
我们提出了一种开发无标记生物传感器检测DNA的新方法。基于生物功能化双倾斜光纤布拉格光栅的生物传感器将DNA的存在转化为其干涉光谱条纹可见性的变化。实时光谱测量结果表明,10nM的DNA溶液诱导10%的相应条纹可见性调制。
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