Vessel segmentation and analysis in laboratory skin transplant micro-angiograms

A. Condurache, T. Aach, S. Grzybowski, H. Machens
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引用次数: 13

Abstract

The success of skin transplantations depends on the adequate revascularization of the transplanted dermal matrix. To induce vessel growth or angiogenesis, pharmacological substances may be applied to the dermal matrix. The effectiveness of different such substances has been evaluated in laboratory experiments. For this purpose, the surface and length of newly grown vessels have to be measured in micro-angiograms (x-ray images of the blood vessels recorded after the injection of a radiopaque substance) of tissue transplanted on the back of laboratory animals. To this end we describe in this contribution a vessel analysis environment central to which is a vessel segmentation tool for surface quantification in fasciocutaneous skin transplant micro-angiograms.
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实验室皮肤移植微血管造影中的血管分割与分析
皮肤移植的成功取决于移植的真皮基质是否有足够的血运重建。为了诱导血管生长或血管生成,可将药理物质应用于真皮基质。不同这类物质的有效性已在实验室实验中进行了评估。为此,必须在移植到实验动物背部的组织的微血管造影(注射不透射线物质后记录的血管的x射线图像)中测量新生血管的表面和长度。为此,我们在本贡献中描述了一个血管分析环境,其中心是用于筋膜皮肤移植微血管造影表面量化的血管分割工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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