Measuring Exposome Associated with Health

Fengyu Zhang, D. Mattison
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Abstract

The concept of exposome has received increasing discussion, including the recent Special Issue of Science –"Chemistry for Tomorrow's Earth,” about the feasibility of using high-resolution mass spectrometry to measure exposome in the body, and tracking the chemicals in the environment and assess their biological effect. We discuss the challenges of measuring and interpreting the exposome and suggest the survey on the life course history, built and ecological environment to characterize the sample of study, and in combination with remote sensing. They should be part of exposomics and provide insights into the study of exposome and health.
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测量与健康有关的暴露量
暴露体的概念受到了越来越多的讨论,包括最近的《科学》特刊——“明日地球的化学”,讨论了使用高分辨率质谱法测量体内暴露体、追踪环境中的化学物质并评估其生物效应的可行性。我们讨论了暴露量测量和解释所面临的挑战,并建议对研究样本的生活史、建筑和生态环境进行调查,以表征研究样本,并与遥感相结合。它们应该是暴露学的一部分,并为暴露与健康的研究提供见解。
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