Risk Factors of Fetal/Infant Outcome in Pregnant Women with Cancer in East Java Indonesia: Epidemiological Study

Nardeen Adel Mekhail Naoum, Ernawati Darmawan
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Abstract

Background: Cancer during pregnancy is a rare event, despite its rarity, its incidence nowadays keeps on increasing worldwide. Objective: This study aims to describe the available data on pregnant women with cancer in East Java- Indonesia, maternal outcomes and fetal outcomes, and knowing the risk factors of bad fetal outcomes in pregnant women with cancer from an epidemiological point of view. Method: This is a quantitative observational study of pregnant women with cancer in East Java Indonesia. Its design is a Cross-sectional study. Data collection was obtained from secondary data (the medical report in the Obgyn department at Dr. Seotomo Hospital from 2016 – 2020). Data were analyzed statistically by using SPSS program version 25. Result: The results showed that from 2016 to 2020, 54 cases of pregnant women with cancer had been extracted with an incident rate 0.8%. The incident rate of Non-Obgyn Cancer (55.6%) is higher than Obgyn Cancer (44.4%). The highest incident rates in non-Obgyn Cancer are Breast cancer (7.5%) and Leukemia (3.7%), while the highest incident rates in Obgyn Cancer are Cervical and Ovarian (8.4%). There was no relationship between cancer type and fetal outcomes, while there is a relationship between cancer stage and fetal outcomes. Conclusion: Cancer stage could be risk factor for fetal outcomes in Indonesian pregnant women with cancer.
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印度尼西亚东爪哇孕妇癌症胎儿/婴儿结局的危险因素:流行病学研究
背景:妊娠期癌症是一种罕见的事件,尽管罕见,但其发病率在世界范围内呈上升趋势。目的:本研究旨在描述印度尼西亚东爪哇地区癌症孕妇的现有资料、孕产妇结局和胎儿结局,并从流行病学角度了解癌症孕妇不良胎儿结局的危险因素。方法:这是一项对印度尼西亚东爪哇孕妇癌症的定量观察研究。它的设计是一个横断面研究。数据收集来自二手数据(2016 - 2020年Dr. Seotomo医院妇产科的医疗报告)。数据采用SPSS软件25版进行统计分析。结果:2016 - 2020年,共抽取孕妇肿瘤54例,发生率为0.8%。非妇科肿瘤(55.6%)的发生率高于妇科肿瘤(44.4%)。非妇科癌症中发病率最高的是乳腺癌(7.5%)和白血病(3.7%),而妇科癌症中发病率最高的是宫颈癌和卵巢癌(8.4%)。癌症类型和胎儿结局之间没有关系,而癌症分期和胎儿结局之间有关系。结论:癌症分期可能是印尼癌症孕妇胎儿结局的危险因素。
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