Dislipidemik Hastalarda Az Yağlı ve Az Kolesterollü Diyet Müdahalesinin LDL Alt Grupları Üzerine Etkisi: Epidemiyolojik Gözlemsel Çalışma

Ülger KAÇAR MUTLUTÜRK, Betül Çi̇çek, Fahriye Bayram, F. Doğruel
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Abstract

Aim: According to studies, the individual cardiovascular disease (CVD) risk is predicted and low density lipoprotein cholesterol (LDL cholesterol) sub-group concentration better than LDL cholesterol. High fat and cholesterol intakes are generally considered to pose a risk on CVD. The purpose of this study is to analogize LDL sub-group concentration pre and post a diet with LowFat and LowCholesterol written a prescription to dyslipidemic sicks along 3 months. Material and Methods: Diagnosticated dyslipidemia sicks (n=47) on the part of the endocrinologist were pursued along 3 months via a LowFat, LowCholesterol diet upon a lasting a month basis, on condition that they were proper for each. Before and after dietary intervention periods, biochemical parameters and anthropometric measurements were compared. Results: A sum of 47 participants (15 men and 32 women) with an average age of 48.51±9.86 years were involved. 13 women were at premenopausal and 19 women were at postmenopausal stages of 32 women involved. Small dense LDL (Sd-LDL) decreased from 11.0 (0.0-37.0) mg/dL at the beginning to 7.0 (0.0-68.1) mg/dL after the dietary intervention, but this decline was unimportant (p=0.686). Midbands (MiDC, MidB, MidA) subgroups of intermediate density lipoprotein cholesterol (IDL-cholesterol) declined considerably after dietary interference (p
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目的:根据研究预测个体心血管疾病(CVD)的危险性,低密度脂蛋白胆固醇(LDL胆固醇)亚组浓度优于LDL胆固醇。高脂肪和高胆固醇的摄入通常被认为会增加心血管疾病的风险。本研究的目的是模拟低脂低胆固醇饮食处方前后3个月的低密度脂蛋白亚组浓度。材料和方法:内分泌学家对诊断为血脂异常的患者(n=47)进行了为期3个月的持续一个月的低脂、低胆固醇饮食,条件是他们适合每个人。饮食干预前后,比较生化参数和人体测量值。结果:共纳入47例患者(男15例,女32例),平均年龄48.51±9.86岁。13名妇女处于绝经前19名妇女处于绝经后32名妇女参与其中。小密度LDL (Sd-LDL)由饮食干预前的11.0 (0.0-37.0)mg/dL下降到饮食干预后的7.0 (0.0-68.1)mg/dL,但下降幅度不显著(p=0.686)。中密度脂蛋白胆固醇(idl -胆固醇)中带(MiDC, MidB, MidA)亚组在饮食干预后显著下降(p
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