Molecular pathological analysis in routine diagnostic

Abstract

Molecular pathological examinations in the context of diagnostic analyses of tumour samples cover a broad spectrum of techniques for routine diagnostics. Especially in the last few years, there has been an increase in a large number of new biomarkers, the investigation of which is of great importance for therapy decision but also for accurate diagnosis. At the same time, the available amount of tissue is getting more and more limited due to different reasons: 1. The change in surgical procedure from large resections to tiny little biopsies; 2. The increasing number of markers which has to be tested on this limited material, e. g. by immunohistochemical stainings.