Overview of selected seminal optical science and photonics processes in nature

SPIE OPTO Pub Date : 2016-03-18 DOI:10.1117/12.2217476
R. Alfano
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Abstract

This presentation gives an overview on some of seminal research in optical science, condensed matter physics, biophysics, biology, biomedical, nonlinear optics, and structure light propagation and interactions at CCNY and GTE Labs over past 46 years. The advent of ultrafast laser pulses with picosecond and femtosecond pulses and optical spectroscopy (label free native fluorescence and Raman) has led to unravel some of mysteries in the molecular world leading to breakthroughs in various areas of science and medicine. The following topics are discussed: white light continuum called now Supercontinuum (SC); first direct measurement of Optical Phonon’s lifetimes; first observation of creation of daughter vibrations in time from excited mother vibration in liquids; first direct measurement of creation and decay of Spin Angular Momentum of electrons in GaAs where picosecond Circular Polarized Light carrying Optical Spin Angular Momentum is generated; Pulse break up into ballistic, snake and diffusive components in scattering media such as um beads and tissues; and use of optical spectroscopy for first cancer detection in label free tissues. Most recently, advances in Biomedical Optics showed that Tryptophan as a key biomarker for aggressive cancers; there are three new optical windows with the Golden window #3 the best for penetrating tissue from 1600 nm to 1800 nm; Complex light with OAM offers potential deeper tissue penetration and Resonance Raman excited using magic 532 nm wavelength in tissues.
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概述选定的重要光学科学和光子学过程在自然界
本报告概述了CCNY和GTE实验室在过去46年中在光学科学、凝聚态物理、生物物理、生物学、生物医学、非线性光学、结构光传播和相互作用等方面的一些开创性研究。具有皮秒和飞秒脉冲的超快激光脉冲以及光谱学(无标签天然荧光和拉曼)的出现,已经揭开了分子世界中的一些谜团,从而在科学和医学的各个领域取得了突破。讨论了以下主题:白光连续体现在称为超连续体(SC);首次直接测量光学声子的寿命;首次观察到在时间上由液体中受激母振动产生子振动;首次直接测量了携带自旋角动量的皮秒圆偏振光在GaAs中产生的电子自旋角动量的产生和衰减;脉冲在微球和组织等散射介质中分解成弹道、蛇形和扩散分量;利用光谱学对无标签组织进行首次癌症检测。最近,生物医学光学的进展表明色氨酸是侵袭性癌症的关键生物标志物;有三种新的光学窗口,其中黄金窗口#3在1600 nm至1800 nm范围内穿透组织的效果最好;复合光与OAM提供潜在的更深的组织穿透和共振拉曼在组织中使用神奇的532nm波长激发。
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