A Study of Passive Microfluidic Mixers

P. Chiarot, R. Mrad, P. Sullivan
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引用次数: 5

Abstract

Three designs of passive microfluidic mixers (fabricated using Micralyne Protolyne technology on a glass substrate) are studied and compared to a basic straight channel diffusion mixer. The designs are analyzed under continuous and pulsating flow conditions using numerical and experimental tools; specifically finite element analysis and particle image velocimetry. Testing and analysis are performed at pressures that can be generated using reciprocating membrane micropumps integrated into a Micro Total Analysis System. It is determined that one of the proposed mixer concepts outperforms all of the other designs considered and enhanced mixing is achieved under pulsating flow. Performance is judged based on criteria that describes the amount of mixing performed, the concentration uniformity at the outlet of the mixer, and the net flow rate. Recommendations are made on how to improve the overall performance of the passive micromixers.
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被动微流控混合器的研究
研究了三种被动式微流控混合器的设计(在玻璃基板上采用微流控protoolyne技术制造),并与基本直通道扩散混合器进行了比较。利用数值和实验工具对连续流和脉动流条件下的设计进行了分析;特别是有限元分析和粒子图像测速。测试和分析是在压力下进行的,可以使用集成在微全分析系统中的往复膜微泵产生压力。确定提出的混合器概念之一优于所有考虑的其他设计,并且在脉动流下实现了增强的混合。性能是根据描述混合量、混合器出口浓度均匀性和净流量的标准来判断的。对如何提高无源微混频器的整体性能提出了建议。
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