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2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)最新文献

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A Novel MEMS Tunable Capacitor 一种新型MEMS可调谐电容器
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.15
Siyuan He, R. Mrad
A novel MEMS tunable capacitor with a high tuning ratio is presented in this paper. The novel tunable capacitor consists of two parallel electrodes, i.e., fixed and moving electrodes and six bi-directional electrostatic actuators, which are able to produce both attractive and repulsive force to drive the moving electrode. So the novel tunable capacitor is able to move in both directions, up and down, away form its static position and therefore achieve a large tuning ratio. Numerical simulations are used to verify the working principle of the novel tunable capacitor and predict that a tuning ratio of 3:1 can be achieved at a driving voltage of 16 volts.
提出了一种具有高调谐比的新型MEMS可调谐电容器。该新型可调谐电容器由两个平行电极组成,即固定电极和运动电极,以及6个双向静电致动器,这些致动器能够产生吸引力和排斥力来驱动运动电极。因此,新型可调谐电容器能够在上下两个方向上移动,远离其静态位置,从而实现大的调谐比。通过数值仿真验证了新型可调谐电容器的工作原理,并预测在16伏驱动电压下可实现3:1的调谐比。
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引用次数: 7
Closed Loop Micromanipulators for Optical Metrology 用于光学计量的闭环微机械臂
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.43
L. Phong, J. Lee, I. Ressejac, M. Maszkiewicz, W. Zheng, S. Crisan, L. L. Noc, F. Picard, H. Jerominek
The use of light beam micromanipulators in space subsystems has received particular attention in recent years. To compensate for changes in system parameters during the flight, these devices require closed loop control. This paper reports on an integrated feedback mechanism devised for flexural tortional devices. It consists in using monolithically embedded photodetectors to measure the portion of incident light crossing an aperture created in the manipulator. The manipulator position is determined from the detector section shadowed by the displaced aperture. A model is presented for the electrostatically actuated manipulator, predicting effects of structural parameters on angular displacement and resolution. As proof of concept, photodiode assisted closed loop manipulators were microfabricated in varying configurations on Si wafer. Their characteristics of deflection versus actuation voltage were better than those predicted by the model. The feedback mechanism was validated in light of the good agreement between differential photocurrents measured from contiguous photodiodes and theoretical prediction. Details on device modeling, microfabrication, and characterization are reported.
近年来,在空间子系统中使用光束微操纵器受到了特别的关注。为了补偿飞行过程中系统参数的变化,这些装置需要闭环控制。本文报道了一种用于弯曲扭转装置的集成反馈机构。它包括使用单片嵌入式光电探测器来测量穿过机械手中创建的孔径的入射光的部分。机械手的位置由被位移孔径遮挡的检测器部分确定。建立了静电驱动机械手的模型,预测了结构参数对角位移和分辨率的影响。作为概念的证明,光电二极管辅助闭环机械手在硅片上以不同的构型进行了微加工。它们的偏转特性与驱动电压的关系比模型预测的要好。根据连续光电二极管测量的差分光电流与理论预测的良好一致性,验证了反馈机制。详细的器件建模,微加工和表征报告。
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引用次数: 0
Micro Digital Sun Sensor: System in a Package 微型数字太阳传感器:系统在一个包
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.92
C. Boom, J. Leijtens, L. V. Duivenbode, N. V. D. Heiden
A novel micro Digital Sun Sensor ( µDSS) is under development in the frame of a micro systems technology (MST) development program (Microned) from the Dutch Ministry of Economic Affairs. Use of available micro system technologies in combination with the implementation of a dedicated solarcell for power supply and a wireless link for data communication allows TNO TPD to develop a truly autonomous and wireless sun sensor. Such a "system in a package" is small enough to be flown on a microsatellite [4]. Although several technical challenges still exist, it seems feasible to build a sensor that will be at least one order of magnitude lower in weight as compared to the current generation sensors (<30 grams) and consumes no external power. These characteristics allow it to fly this sensor on satellites that are so small that inclusion of a fine sun sensor until now has not been feasible.
一种新型微型数字太阳传感器(µDSS)正在荷兰经济部的微系统技术(MST)开发计划(micronon)的框架内开发。利用现有的微系统技术,结合专用太阳能电池的供电和无线链路的数据通信,使TNO TPD能够开发出真正自主的无线太阳传感器。这种“封装系统”足够小,可以在微型卫星上飞行。尽管仍然存在一些技术挑战,但与当前一代传感器(<30克)相比,制造一种重量至少降低一个数量级且不消耗外部电源的传感器似乎是可行的。这些特性使它能够在卫星上飞行,这些卫星非常小,直到现在还不可能包含一个精细的太阳传感器。
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引用次数: 30
Grammatical Self Assembly for Planar Tiles 平面瓷砖的语法自组装
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.76
R. Ghrist, D. Lipsky
We introduce a formal grammatical process for planar self-assembling systems with conformal switching which instantiates the geometry of the tiles. This extends prior work which gave a grammatical structure that models only the topology of the assembly. The addition of geometric data leads to the problem of determining which sets of grammatical rules preserve the planar constraint. We illustrate global obstructions while generating examples of rule sets which intrinsically force the preservation of planar geometry.
我们介绍了一个具有共形转换的平面自组装系统的形式化语法过程,它实例化了瓷砖的几何形状。这扩展了先前的工作,该工作给出了仅模拟组装拓扑结构的语法结构。几何数据的添加导致了确定哪些语法规则集保留平面约束的问题。我们在生成规则集的例子的同时说明了全局障碍,这些规则集本质上强制保持平面几何。
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引用次数: 7
Analytical Modeling and Quantitative Analysis of Scratch Drive Actuator 划痕驱动作动器的解析建模与定量分析
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.32
J. Zu, Q. Qu, G. Cheng
A new analytical model of Scratch Drive Actuator (SDA) is proposed, which considers its deforming states and geometry characteristics. This model contains three kinds of conditions: low driving voltage, critical driving voltage and high driving voltage. The storing strain energy in the SDA is studied under different conditions because the working performance of the SDA mainly depends on it. Analysis results demonstrate that it is necessary to choose appropriate design parameters of the SDA so that the SDA works near the critical state. Finally, discussions and suggestions for the design of SDA are presented in this paper.
提出了一种考虑挠性驱动器变形状态和几何特性的挠性驱动器解析模型。该模型包含低驱动电压、临界驱动电压和高驱动电压三种工况。由于SDA的工作性能主要取决于它的应变能存储,因此研究了SDA在不同条件下的应变能存储。分析结果表明,有必要选择合适的SDA设计参数,使SDA工作在临界状态附近。最后,对SDA的设计进行了讨论和建议。
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引用次数: 9
A Study of Passive Microfluidic Mixers 被动微流控混合器的研究
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.23
P. Chiarot, R. Mrad, P. Sullivan
Three designs of passive microfluidic mixers (fabricated using Micralyne Protolyne technology on a glass substrate) are studied and compared to a basic straight channel diffusion mixer. The designs are analyzed under continuous and pulsating flow conditions using numerical and experimental tools; specifically finite element analysis and particle image velocimetry. Testing and analysis are performed at pressures that can be generated using reciprocating membrane micropumps integrated into a Micro Total Analysis System. It is determined that one of the proposed mixer concepts outperforms all of the other designs considered and enhanced mixing is achieved under pulsating flow. Performance is judged based on criteria that describes the amount of mixing performed, the concentration uniformity at the outlet of the mixer, and the net flow rate. Recommendations are made on how to improve the overall performance of the passive micromixers.
研究了三种被动式微流控混合器的设计(在玻璃基板上采用微流控protoolyne技术制造),并与基本直通道扩散混合器进行了比较。利用数值和实验工具对连续流和脉动流条件下的设计进行了分析;特别是有限元分析和粒子图像测速。测试和分析是在压力下进行的,可以使用集成在微全分析系统中的往复膜微泵产生压力。确定提出的混合器概念之一优于所有考虑的其他设计,并且在脉动流下实现了增强的混合。性能是根据描述混合量、混合器出口浓度均匀性和净流量的标准来判断的。对如何提高无源微混频器的整体性能提出了建议。
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引用次数: 5
Preliminary Results of Nanopharmaceuticals Used in the Radioimmunotherapy of Ovarian Cancer 纳米药物用于卵巢癌放射免疫治疗的初步结果
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.126
S. McQuarrie, G. Miller, Mavanur R. Suresh, John R. Mercer
A multistep radioimmunotherapeutic (RIT) approach, exploiting the combination of a bispecific monoclonal antibody (BsMAb) with 90Y labelled biotinylated long-circulating liposomes was tested as a potential adjuvant treatment for epithelial ovarian carcinomatosis. The BsMAb, with anti-CA 125 and anti-biotin epitopes was used with PEGylated liposomes coated with biotin to deliver the cytotoxic radionuclide 90Y to tumor sites. This approach was used to overcome some of the major obstacles associated with conventional strategies, in particular, to increase the amount of radioactivity delivered to the tumor site compared with conventional monoclonal antibody (MAb) radionuclide delivery. Sequential intraperitoneal administration of the targeting and therapeutic moieties provides the basis for enhanced therapeutic ratio, according to our strategy. We report here the results of an in vivo therapy using our RIT approach with the Balb/c nude mouse model xenografted with the NIH:OVCAR-3 (CA 125+) human ovarian cancer cell line. An ongoing tumor growth delay/control study in Balb/c mice xenografted intraperitoneally with the NIH:OVCAR-3 cell line indicates a significant delay in onset of tumor and ascites development in treated vs. control populations.
一种多步骤放射免疫治疗(RIT)方法,利用双特异性单克隆抗体(BsMAb)与90Y标记的生物素化长循环脂质体的组合,作为上皮性卵巢癌病的潜在辅助治疗进行了测试。具有抗ca 125和抗生物素表位的BsMAb与涂有生物素的聚乙二醇化脂质体一起使用,将细胞毒性放射性核素90Y递送到肿瘤部位。这种方法被用来克服与传统策略相关的一些主要障碍,特别是与传统的单克隆抗体(MAb)放射性核素递送相比,增加了传递到肿瘤部位的放射性量。根据我们的策略,靶向和治疗部分的顺序腹腔内给药为提高治疗比率提供了基础。我们在此报告了使用我们的RIT方法对移植了NIH:OVCAR-3 (CA 125+)人卵巢癌细胞系的Balb/c裸鼠模型进行体内治疗的结果。一项正在进行的肿瘤生长延迟/对照研究表明,在NIH:OVCAR-3细胞系的Balb/c小鼠腹腔内异种移植中,治疗组与对照组相比,肿瘤和腹水发展的发病明显延迟。
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引用次数: 39
Nanoparticle Preparation and Its Application — A Nanotechnology Particle Project in Japan 纳米颗粒的制备及其应用&#8212日本的纳米技术粒子项目
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.108
K. Okuyama, W. Lenggoro, Toru Iwaki
Nanoparticles such as metals, semiconductors and metal oxides are of great interest for a wide variety of applications in the field of information, energy, environmental and medical technologies due to their unique or improved properties determined primarily by size, composition and structure along with their self-organized film structures. In this presentation, Japan’s national project on nanoparticle synthesis and its applications in nanotechnology programs is reviewed along with some new findings on synthesis technologies and the related nanoparticle-based nano-structures developed during the project. The synthesis methods include liquid phase, gas phase, liquid-based gas phase such as novel spray methods and sol-gel assisted in-situ techniques and continuous mass production method.
纳米粒子如金属、半导体和金属氧化物在信息、能源、环境和医疗技术领域的广泛应用引起了极大的兴趣,因为它们的独特或改进的性质主要取决于它们的大小、组成和结构以及它们的自组织薄膜结构。在本次演讲中,日本的纳米粒子合成国家项目及其在纳米技术项目中的应用,以及在合成技术和相关纳米粒子基纳米结构项目中开发的一些新发现。合成方法包括液相法、气相法、液基气相法等新颖的喷雾法和溶胶-凝胶辅助原位技术及连续量产法。
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引用次数: 15
An Optimized Micromixer with Patterned Grooves 一种优化的带花纹凹槽的微混频器
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.30
Yanghua Tang, Q. M. Wu, E. Czyzewska, K. Stanley
With the development of microfluidic systems, there is a growing interest in micro scale laminar flow mixing. In this work, the fluid rotating angle and mixing efficiency in a micromixer with patterned grooves are studied as a function of the dimensions of the microstructure by numerical simulation. We found that mixing efficiency does not always increase with higher fluid stream rotation in the microchannel. High groove aspect ratios are not advantageous to fluid rotation. Experiments on mixture of two fluids were done on a micromixer fabricated in PDMS by replica molding. An 85% mixing efficiency was obtained in a 30mm long mixing channel with two dyed liquids.
随着微流体系统的发展,人们对微尺度层流混合越来越感兴趣。本文通过数值模拟研究了带花纹槽的微混合器中流体旋转角和混合效率随微结构尺寸的变化规律。研究发现,微通道内的流体转速越大,混合效率并不一定越高。高沟槽长径比不利于流体旋转。采用复模法在PDMS材料制备的微混合器上进行了两种流体的混合实验。两种染色液在30mm长的混合通道中混合效率达到85%。
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引用次数: 7
Effect of Superhydrophobic Surfaces for Wetting in Micro-Systems 超疏水表面对微系统润湿的影响
Pub Date : 2004-08-25 DOI: 10.1109/ICMENS.2004.58
W. Li, R. Mohamadi, A. Amirfazli
To develop energy efficient microfluidic systems it is important to minimize the adhesion of the liquid to the surfaces in the system. One of the proposed methods in the literature is to use superhydrophobic surfaces, i.e. surfaces with contact angles above 150 degrees (for water). However, the issue that is not generally considered in depth in literature is the role of contact angle hysteresis (the difference between advancing and receding contact angles). In other words, to have an energy efficient droplet actuation system for microfluidics it is not sufficient to use surfaces that have large contact angles, but they also should have low contact angle hysteresis (CAH). Contact angle hysteresis is a common phenomenon in wetting. It is important but difficult to theoretically investigate CAR to optimally design superhydrophobic surfaces for micro-systems. We will present a universal approach to calculate CAR based on a free energy analysis for micro-textured surfaces. Thermodynamic status of contact angles and calculation of free the energy barrier are significantly simplified by using a representative 2D model instead of a 3D model with minimum loss of generality. A pillar surface structure is chosen as a typical example (see Figure 1). It is demonstrated that this approach can predict CAR and equilibrium contact angles that are consistent with predictions of Wenzel's and Cassie's equations. This approach can also provide a criterion for transition between noncomposite and composite structures (i.e. free spreading of liquids on a surface or achieving minimum contact area between a liquid drop and surfaces in a channel). Recent experimental results for wetting of superhydrophobic surfaces will also be discussed.
为了开发高效节能的微流体系统,重要的是要尽量减少液体对系统表面的粘附。文献中提出的方法之一是使用超疏水表面,即接触角超过150度的表面(对于水)。然而,文献中普遍没有深入考虑的问题是接触角滞后的作用(前后接触角的差异)。换句话说,要实现高效的微流体液滴驱动系统,仅使用具有大接触角的表面是不够的,而且还应具有低接触角迟滞(CAH)。接触角滞后是润湿过程中常见的现象。从理论上研究CAR对微系统超疏水表面的优化设计是很重要但困难的。我们将提出一种基于微纹理表面的自由能分析来计算CAR的通用方法。采用具有代表性的二维模型代替三维模型,极大地简化了接触角的热力学状态和自由能垒的计算,使通用性损失最小。选择一个柱状表面结构作为典型的例子(见图1)。结果表明,该方法可以预测与Wenzel和Cassie方程预测一致的CAR和平衡接触角。该方法还可以提供非复合和复合结构之间过渡的标准(即液体在表面上的自由扩散或在通道中液滴和表面之间实现最小接触面积)。本文还将讨论超疏水表面润湿的最新实验结果。
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引用次数: 0
期刊
2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04)
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