Environmental and Occupational Epidemiology Principles

E. Velonakis
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引用次数: 2

Abstract

Occupational epidemiology studies the distribution of health events and health related determinants and its relation to the working environment. Environmental epidemiology focuses on the involuntary exposure to physical and chemical factors in the indoor or outdoor environment that may affect health patterns. Occupational and environmental epidemiology use similar methodology although the conditions differ. The environmental epidemiology studies beyond the health effect of exposure to specific environmental factors and must consider the long-term impact of the ecosystems to nearby populations. Molecular technologies allow the detection of effects at the molecular level originated by very low levels of exposure. The concept of an exposome is a kind of database with information concerning environmental exposure measurements in a life time and corresponding biomarkers concentrations in different biospeciments, considering internal individual genetic characteristics.
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环境和职业流行病学原理
职业流行病学研究健康事件和健康相关决定因素的分布及其与工作环境的关系。环境流行病学侧重于不自觉地接触可能影响健康模式的室内或室外环境中的物理和化学因素。职业流行病学和环境流行病学使用类似的方法,尽管条件不同。环境流行病学研究超出了暴露于特定环境因素对健康的影响,必须考虑生态系统对附近人口的长期影响。分子技术可以在分子水平上检测极低水平暴露所产生的影响。暴露体的概念是考虑个体内部遗传特征,包含一生中环境暴露测量和不同生物标本中相应生物标志物浓度信息的数据库。
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