Bioactive Peptides from Agriculture and Food Industry Co-Products: Peptide Structure and Health Benefits

J. Yongsawatdigul, A. Hamzeh
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引用次数: 1

Abstract

Co-products from food processing are typically disposed or turned into low value animal feed. Proteinaceous co-products can be converted to bioactive peptides exerting health benefits, which can lead to development of nutraceuticals and functional foods. This is an effective means for valorization of these co-products. The release of encrypted peptides exhibits various bioactivities, including antihypertension, antioxidant, immunomodulatory activities among others, in vitro, and some activities have been demonstrated in vivo. Structure modification of bioactive peptides occurring under gastrointestinal digestion and cellular transport remains the important factor determining the health benefits of bioactive peptides. Understanding peptide transformation in gastrointestinal tract and in blood circulation before reaching the target organs would shed some lights on its bioavailability and subsequently ability to exert physiological impact. In this chapter, the potential health promoting properties of peptides encrypted in various sources of co-products will be reviewed based on evidence on in vitro, in vivo and clinical trial studies. Structural changes of bioactive peptides under physiological condition will also be discussed in relation to its bioactivities.
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农业和食品工业副产品的生物活性肽:肽结构和健康益处
食品加工的副产品通常被处理或变成低价值的动物饲料。蛋白质副产物可以转化为具有健康益处的生物活性肽,从而可以开发营养保健品和功能食品。这是使这些副产物增值的有效手段。加密肽的释放在体外表现出多种生物活性,包括抗高血压、抗氧化、免疫调节等活性,一些活性已在体内得到证实。生物活性肽在胃肠道消化和细胞运输过程中发生的结构修饰仍然是决定生物活性肽健康益处的重要因素。了解肽在到达目标器官之前在胃肠道和血液循环中的转化将有助于揭示其生物利用度和随后发挥生理影响的能力。在本章中,将根据体外、体内和临床试验研究的证据,对不同来源的副产物中加密的肽的潜在健康促进特性进行综述。生物活性肽在生理条件下的结构变化也与其生物活性有关。
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