Diagnostics of haemostasis efficiency with laser illumination scattering pattern analysis

Abstract

Laser illumination scattering by blood samples during the thrombus formation and corresponding changes in scattering patterns for visible spectral range have been studied. Diode laser emission bands with central wavelengths of 0.63, 0.50 and 0.40 μm have been utilized in the single-source and combined illumination configurations. Dynamics of the scattering pattern in terms of its central spot characteristic size has been analyzed and referenced with histological examination. The obtained results demonstrate the applicability of the scattering pattern analysis for assessment of the blood clot formation stage. The prospects for practical diagnostics of the haemostasis efficiency in the emergency medicine with the help of the proposed method have been discussed.