Explainable Deep Learning for Medical Image Segmentation With Learnable Class Activation Mapping

Kaiyu Wang, Sixing Yin, Yining Wang, Shufang Li
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Abstract

Medical image segmentation is crucial for facilitating pathology assessment, ensuring reliable diagnosis and monitoring disease progression. Deep-learning models have been extensively applied in automating medical image analysis to reduce human effort. However, the non-transparency of deep-learning models limits their clinical practicality due to the unaffordably high risk of misdiagnosis resulted from the misleading model output. In this paper, we propose a explainability metric as part of the loss function. The proposed explainability metric comes from Class Activation Map(CAM) with learnable weights such that the model can be optimized to achieve desirable balance between segmentation performance and explainability. Experiments found that the proposed model visibly heightened Dice score from to , Jaccard similarity from to and Recall from to respectively compared with U-net. In addition, results make clear that the drawn model outdistances the conventional U-net in terms of explainability performance.
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基于可学习类激活映射的医学图像分割的可解释深度学习
医学图像分割对于促进病理评估、确保可靠诊断和监测疾病进展至关重要。深度学习模型已广泛应用于医学图像的自动化分析,以减少人工的工作量。然而,深度学习模型的不透明性限制了其临床实用性,因为误导性模型输出导致的误诊风险高得难以承受。在本文中,我们提出了一个可解释性度量作为损失函数的一部分。所提出的可解释性度量来自具有可学习权重的类激活图(Class Activation Map, CAM),从而可以优化模型以实现分割性能和可解释性之间的理想平衡。实验发现,与U-net相比,该模型显著提高了骰子得分从0到0、纸牌相似度从0到0和召回率从0到0。此外,结果表明,绘制的模型在可解释性性能方面优于传统的U-net。
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