Clinical Spectrum- Cognition, Stages, Functionality among Elderly with Dementia: A Cross-Sectional Study

Niju Niroula
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Abstract

Introduction: Although cognitive and functional impairment are the hallmark features of Dementia but it is often undetected and neglected as a normal part of aging. So we conducted this study on clinical profile of dementia patients. Aims: The aim of this study is to evaluate the Patient’s cognitive impairment, functional capacities, and stages of severity of dementia. Methods: A descriptive cross sectional study was conducted among 50 patients aged 60 years and above, of both sexes with the diagnosis of Dementia, admitted in Medicine ward of Nepalgunj Medical College, Nepalgunj, Nepal. The screening of dementia was done using Mini-Mental State Examination tool and the diagnosis of Dementia was confirmed using the International Classification of Disease-10 Diagnostic Criteria for Research. Cognition, functionality and stages of severity of dementia were assessed using Hierarchic Dementia Scale, Functional Autonomy Measurement System, Functional Assessment Staging Test tools respectively. Results: Among a total of 50 dementia patients, the mean and standard deviation of age was 82.4±6.1 years, majority of cases 60 % were in the age group ≥85 years and most patients were female 56%. The mean Mini-Mental State Examination score was 9.6±3.0, and 50 % had severe impairment of cognition on Hierarchic Dementia Scale. Stage 7 dementia 32 % was most prevalent stage on Functional Assessment Staging and severe deterioration in the functional autonomy was seen in 54% dementia patients (score ≥41 on Functional Autonomy Measurement System). Conclusion: This study concludes that significant number of elderly patients attending tertiary care hospital suffers from dementia with severe impairment in cognition and functionality in various stages of dementia in the elderly patients.
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临床谱-老年痴呆患者的认知、分期、功能:一项横断面研究
虽然认知和功能障碍是痴呆症的标志性特征,但作为衰老的正常组成部分,它往往未被发现和忽视。所以我们对痴呆患者的临床特征进行了研究。目的:本研究的目的是评估患者的认知障碍、功能能力和痴呆严重程度的阶段。方法:对尼泊尔尼泊尔君医学院内科病房收治的50例60岁及以上、男女均为痴呆的患者进行描述性横断面研究。痴呆的筛查使用迷你精神状态检查工具,痴呆的诊断使用国际疾病分类10诊断标准进行研究。分别采用痴呆分级量表、功能自主测量系统、功能评估分期测试工具对痴呆患者的认知、功能和严重程度进行评估。结果:50例痴呆患者中,年龄的平均值和标准差为82.4±6.1岁,年龄≥85岁者占60%,女性占56%。平均精神状态检查评分为9.6±3.0分,50%的患者存在严重的认知障碍。7期痴呆32%是功能评估分期中最常见的阶段,54%的痴呆患者功能自主严重恶化(功能自主测量系统评分≥41分)。结论:三级医院住院的老年痴呆患者在痴呆的各个阶段均存在严重的认知和功能障碍。
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