Synthetic Studies of Vitamin B12

Abstract

Overall these are selections from the total synthesis of vitamin B12. Through the use of selected reactions in the reaction schema, hypothetical mechanisms have been provided. It is the hope of the author, that it will provide insight for students in organic chemistry. Additionally the focus was on the Eschenmoser’s Variant of the total synthesis of vitamin B12. This required the reviewing of the lectures of Dr. A. Eschenmoser as well as reviews of the different mechanistic process involved. Due to constraints all of the mechanisms have not been developed, but selected ones have been provided and shown for understanding.