Antisense homology boxes coincide with the "hot spot" regions predicted by resonant recognition theory

L. Baranyi, Irena Cosic, W. Campbell, E. Deretey, Viorica Deretey, Noriko Okada, H. Okada
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引用次数: 3

Abstract

Recent findings indicate that two novel theories, the Molecular Recognition Theory (MRT) based on the structure of the genetic code and on a novel motif termed antisense homology box, found in proteins and the Resonant Recognition Model, (RRM theory) based on resonant energy distribution of delocalised electrons between classes of proteins having similar functions may have common roots. The authors found that in contrast to a statistically expected 20% of overlap in the regions involved in the antisense homology boxes and hot "spots" predicted by RRM there is more than 60% prevalence of co-localization in proteins analyzed so far.
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反义同源盒与共振识别理论预测的“热点”区域重合
最近的研究结果表明,两种新的理论,基于遗传密码结构和反义同源盒的分子识别理论(MRT)和基于具有相似功能的蛋白质之间的离域电子共振能量分布的共振识别模型(RRM理论)可能有共同的根源。作者发现,与RRM预测的反义同源盒和热点区域的重叠率为20%的统计预期相反,到目前为止分析的蛋白质中共定位的发生率超过60%。
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