{"title":"Pharmacological interventions for cognitive dysfunction","authors":"B. Baune","doi":"10.1093/med/9780198835554.003.0007","DOIUrl":null,"url":null,"abstract":"The chapter Pharmacological interventions for cognitive dysfunction in major depressive disorder (MDD) reviews a broad range of antidepressants that show differential efficacy in exerting improving and impairing effects on cognitive function in MDD, as well as potential side-effects on cognition. The chapter explores new targets and pharmacological agents that are under increasing investigation for cognitive effects in MDD. It identifies methodological challenges of cognition trials in MDD that need to be overcome to improve the evidence base. To conclude, it highlights results from new network meta-analyses on the relative effects of antidepressants on cognitive function assessed with commonly used cognitive tests.","PeriodicalId":334522,"journal":{"name":"Cognitive Dimensions of Major Depressive Disorder","volume":"8 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cognitive Dimensions of Major Depressive Disorder","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/med/9780198835554.003.0007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
The chapter Pharmacological interventions for cognitive dysfunction in major depressive disorder (MDD) reviews a broad range of antidepressants that show differential efficacy in exerting improving and impairing effects on cognitive function in MDD, as well as potential side-effects on cognition. The chapter explores new targets and pharmacological agents that are under increasing investigation for cognitive effects in MDD. It identifies methodological challenges of cognition trials in MDD that need to be overcome to improve the evidence base. To conclude, it highlights results from new network meta-analyses on the relative effects of antidepressants on cognitive function assessed with commonly used cognitive tests.
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