Prospective Clinicopathological Study of Penile Cancer Patients : A Single Institution Experience

Abstract

Background: Carcinoma of the penis is an uncommon malignancy in Western countries but constitutes amajor health problem in many countries in Asia, Africa, and South America, where it may comprise up to10% of all malignancies.Materials and Method: 42 consecutive patients of carcinoma penis were treated from 2013 to 2015. Clinicaland pathological profies were recorded and studied prospectively.Results: 20/42 (48%) patients were of the age group 60 and above. majority of patients belonged to poorsocioeconomic status, 32/42 patients(76.1%). Glans of the penis was the most common site of presentationin 28/42patients(66.6%). The most common symptoms were pus discharge from the penile ulcer in 21patients(50%). 31/42 patients were chronic smoker or tobacco chewer. Inguinal lymph nodes were palpablein 24/42 (57%). The most common complication associated with Groin node dissection was lymphedema in19 patients (45.2%). 12/42 patients had inguinal lymph node metastasis in final histopathological examinationreport. 50 % patients had grade II primary tumor.Conclusion: Incidence of carcinoma penis peaks in the 6thdecade of life. Illiteracy, low socio-economicstatus and phimosis appear to be main predisposing factors for carcinoma of penis. Nodal metastasis wassignificantly associated with factors like T3 and high grade lesions (grade II & III). Complication rate relatedto groin node dissection is high, commonest being lymphedema.