Multi-Droplet Routing based on a Shape-Dependent Velocity Model on MEDA Biochips

Chiharu Shiro, Hiroki Nishikawa, Xiangbo Kong, Hiroyuki Tomiyama, Shigeru Yamashita
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Abstract

Digital microfluidic biochips (DMFB) have attracted attention in the biochemical and medical industries. A micro electrode dot array (MEDA) biochip reduces limitations of DMFB which have limitations on droplet size, shape, direction of movement, and sensor. In particular, it is known that the droplet moves at a different velocity model if the shape is changed. However, routing of multiple droplets at the same time with shape-dependent velocities has not been considered in the past. In this paper, we propose a multi-droplet routing technique for MEDA biochips with shape-dependent velocity of droplets. The proposed technique takes the advantage of velocities dependent on the shapes and aim to reduce the overall routing time of droplets from sources to destinations. Simulation results show that the proposed technique shortens the routing time by 90% on average compared to the state-of-the-art technique.
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MEDA生物芯片上基于形状相关速度模型的多液滴路径
数字微流控生物芯片(DMFB)在生物化学和医学领域受到广泛关注。微电极点阵列(MEDA)生物芯片减少了DMFB在液滴大小、形状、运动方向和传感器方面的限制。特别是,已知液滴在形状改变时以不同的速度模型运动。然而,过去并没有考虑到多个液滴同时以形状相关的速度运动。在本文中,我们提出了一种具有液滴形状依赖速度的MEDA生物芯片的多液滴布线技术。所提出的技术利用依赖于形状的速度的优势,旨在减少液滴从源头到目的地的总体路径时间。仿真结果表明,与现有的路由算法相比,该算法平均缩短了90%的路由时间。
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