Alberto Zeni, M. Crespi, Lorenzo Di Tucci, M. Santambrogio
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引用次数: 6
Abstract
In the current years broad access to genomic data is leading to improve the understanding and prevention of human diseases as never before. De-novo genome assembly, represents a main obstacle to perform the analysis on a large scale, as it is one of the most time-consuming phases of the genome analysis. In this paper, we present a scalable, high performance and energy efficient architecture for the alignment step of SSPACE, a state of the art tool used to perform scaffolding also in case of de-novo assembly. The final architecture is able to achieve up to 9.83x speedup in performance when compared to the software version of Bowtie, a state of the art tool used by SSPACE to perform the alignment.
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