{"title":"Cramér Rao bound analysis of joint B1/T1 mapping methods in MRI","authors":"A. Funai, J. Fessler","doi":"10.1109/ISBI.2010.5490075","DOIUrl":null,"url":null,"abstract":"In MRI, RF field inhomogeneity (B<inf>1</inf>) and relaxation effects (T<inf>1</inf>) significantly affect both B<inf>1</inf> and T<inf>1</inf> mapping. Simultaneous joint estimation of both B<inf>1</inf> and T<inf>1</inf> has the potential to greatly improve both B<inf>1</inf> and T<inf>1</inf> estimation. This paper analyzes the Cramér Rao Bound for joint B<inf>1</inf>, T<inf>1</inf> estimation using common B<inf>1</inf> and T<inf>1</inf> pulse sequences. This analysis aids choosing pulse sequences and parameters given desired levels of B<inf>1</inf> and T<inf>1</inf> accuracy and the inherent trade off between the two mappings.","PeriodicalId":250523,"journal":{"name":"2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","volume":"54 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"9","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ISBI.2010.5490075","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 9
Abstract
In MRI, RF field inhomogeneity (B1) and relaxation effects (T1) significantly affect both B1 and T1 mapping. Simultaneous joint estimation of both B1 and T1 has the potential to greatly improve both B1 and T1 estimation. This paper analyzes the Cramér Rao Bound for joint B1, T1 estimation using common B1 and T1 pulse sequences. This analysis aids choosing pulse sequences and parameters given desired levels of B1 and T1 accuracy and the inherent trade off between the two mappings.
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