The Role of Synbiotic in Cobb-strain Broiler Performance Challenged with Campylobacter jejuni as a Substitute for Antibiotic Growth Promotor (AGP)

A. Wahyuni, T. Nahak, M. C. C. Malelak, V. C. Prakasita, S. L. Adrenalin
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Abstract

One of the feed additives that have long been used is Antibiotic Growth Promoter (AGP). But nowadays, the use of AGP as a growth promoter has been banned because it has negative impacts such as antimicrobial resistance. Campylobacter jejuni is a pathogenic bacterium that often infects birds, especially broilers. This research aims to investigate the role of synbiotic composed of a prebiotic, and Saccharomyces sp. and Lactobacillus sp. as probiotics (commercial products) in performance of broilers challenged with C. jejuni as a substitute for AGP. Twenty-one Day Old Chicks (DOC) of Cobb-strain broilers were divided into three groups, each consisting of 7 chicks. Group I was given basal diets, group II was given basal diets and AGP (with 250 g/ton of enramycin), and group III was given basal diets and synbiotic (100 gram/100 kg). C. jejuni challenge test was carried out at the 3 week. The results suggested that at week 4, group III showed more and significantly different body weight from that of group I, but it did not differ significantly from that of group II. Similarly, at week 4 the weight gain of group III was higher and significantly different compared to that of group I, but did not differ significantly from that of group II. Also, the carcass percentage at week 5 did not differ significantly among the groups, but group III had a higher percentage of carcasses than groups I and II. The addition of synbiotic can replace AGP as a feed additive because it can improve the performance of broilers challenged by C. jejuni.
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合成菌替代抗生素生长促进剂(AGP)对cobb型肉鸡生产性能的影响
抗生素生长促进剂(AGP)是长期使用的饲料添加剂之一。但是现在,AGP作为生长促进剂的使用已经被禁止,因为它有诸如抗菌素耐药性等负面影响。空肠弯曲杆菌是一种常感染禽类,尤其是肉鸡的致病菌。本研究旨在探讨由益生元组成的益生菌,以及以酵母菌和乳杆菌为益生菌(商品)的益生菌对空肠梭菌替代AGP攻毒肉鸡生产性能的影响。将21日龄柯布系肉鸡(DOC)分为3组,每组7只。ⅰ组饲喂基础饲粮,ⅱ组饲喂基础饲粮+ AGP(添加250 g/t enramycin),ⅲ组饲喂基础饲粮+合成饲粮(100 g/ 100 kg)。3周时进行空肠梭菌攻毒试验。结果表明,在第4周时,III组的体重与I组相比差异更大且显著,但与II组差异不显著。同样,第4周时,III组的增重高于I组,且与I组有显著差异,但与II组无显著差异。第5周胴体率各组间差异不显著,但ⅲ组胴体率高于ⅰ组和ⅱ组。在肉鸡饲粮中添加合成菌可以提高空肠梭菌侵毒肉鸡的生产性能,可以替代AGP作为饲料添加剂。
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