Assessment of Drug Related Problems in Patients with Cardiovascular Diseases in Tertiary Care Hospital: A Clinical Pharmacist Intervention

Abstract

Drug related problems in cardio vascular disease patients may lead to morbidity, mortality and the decreased quality of life. The main aim of the study is to assess, identify and resolve drug related problems in patients with Cardiovascular Diseases. A total of 150 cardiac patients were enrolled into the study. In our study, out of 150 we got 71 DRPs like Drug-Drug interactions 33(46.4%), ADRs 14(20%), indication without Drug 6(8.4%), drug use without indication 8(11.2%), sub therapeutic dose 10(14%). The association between risk factors like alcohol abuse, smoking, diabetes, hypertension increased risk of CVD. The P value was statistically significant in males than in females. In this study, for individuals with drug related problems of cardiovascular diseases, males were found to be more when compared with females due to risk factors such as smoking, alcoholism, life style etc. the drug related problems were high in patients aged between 40-60 years because of their multiple co-morbid conditions. Polypharmacy was the main predisposing factor for drug related problems.