New Estimation Method of Total Creatine Phosphokinase Release in Early Stage in Acute Myocardial Infarction

T. Kitawaki, H. Oka, S. Usui, S. Hirohata, S. Kusachi
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Abstract

In this paper, we introduce a new estimation method for total creatine phosphokinase release based on a physiological model of the serum creatine phosphokinase (CPK) activity change that can be used to estimate the total CPK release accurately, as early as possible, without frequent blood sampling. The physiological model and a new calculation method were applied to the serum CPK activity change of patients who suffered acute myocardial infarction (AMI). According to the results, the physiological model showed good agreement with the serum CPK activity change and the estimated value of the total CPK release also agreed well with that calculated using the conventional technique with clinically acceptable accuracy.
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急性心肌梗死早期总肌酸磷酸激酶释放的新方法
本文介绍了一种基于血清肌酸磷酸激酶(CPK)活性变化的生理模型估算总肌酸磷酸激酶释放量的新方法,该方法可以在不频繁采血的情况下,尽早准确估算总肌酸磷酸激酶释放量。将建立的生理模型和新的计算方法应用于急性心肌梗死(AMI)患者血清CPK活性的变化。结果表明,生理模型与血清CPK活性变化吻合较好,CPK总释放估计值与常规技术计算值吻合较好,具有临床可接受的准确性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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