Cutaneous aspergillosis in a diabetic patient- A cytological encounter in FNAC

Gourik Gangopadhyay, S. Gautam, Mohd Feroz Alam, Bushra Siddiqui
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Abstract

Diabetes mellitus is a public health problem significantly contributing to morbidity and mortality worldwide. The patients are highly prone to opportunistic infections with major systemic as well as cutaneous fungi. The fungal infections frequent in diabetics include Candidiasis as well as cutaneous Aspergillosis. The most commonly involved species include Aspergillus niger, Aspergillus flavus and Aspergillus fumigatus. Presenting here is a case of 60 years male with history of diabetes mellitus type 2 on oral hypoglycaemic agents, presenting in Medicine Out Patient Department with complaints of progressive painless left cystic medial ankle swelling for last 4 months. Patient was then asked to undergo FNAC which revealed pyogenic inflammation with giant cells and fungal hyphae showing acute angled branching. Furthermore, microbiological confirmation was also done and patient was initiated treatment for the same. This case report underlines the importance of FNAC and Cytological study in the accurate and early diagnosis of Cutaneous Aspergillosis even before the more expensive and time-consuming microbiological diagnostic modalities are applied.
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糖尿病患者皮肤曲霉病- FNAC的细胞学检查
糖尿病是一个公共卫生问题,在世界范围内造成了严重的发病率和死亡率。患者很容易发生主要全身和皮肤真菌的机会性感染。糖尿病患者常见的真菌感染包括念珠菌病和皮肤曲霉病。最常见的种类包括黑曲霉、黄曲霉和烟曲霉。这里有一个60岁的男性,有2型糖尿病病史,服用口服降糖药,在内科门诊部就诊,主诉持续4个月的无痛性左踝关节内侧囊性肿胀。然后要求患者进行FNAC检查,结果显示化脓性炎症,巨细胞和真菌菌丝呈急性角度分支。此外,还进行了微生物学确认,并开始对患者进行治疗。本病例报告强调了FNAC和细胞学研究在准确和早期诊断皮肤曲霉病方面的重要性,甚至在应用更昂贵和耗时的微生物诊断方式之前。
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