Microemulsion Systems: Generalities and Fields of Application

Fernández R. Nathalie, M. German, C. Marianela, Matarrita B. Daniela, Baltodano V. Eleaneth, C. B. Gustavo, Pacheco M. Jorge
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Abstract

Microemulsions are two-phase oil-aqueous systems stabilized by a surfactant/cosurfactant system, formed from the spontaneous self-assembly of hydrophobic or hydrophilic parts of surfactant molecules, essential at the industrial level for their unique properties, improving processes and reducing costs. Their main uses in the pharmaceutical, cosmetic, and food industries are to improve the biopharmaceutical and pharmacokinetic properties of drugs, the skin penetration properties, and the stability and solubility of different ingredients. They are obtained by techniques such as phase inversion and phase titration. They are characterized by different techniques that allow obtaining information on the dynamic properties, droplet size, structural arrangement and orientation, molecular aggregation, and system interactions, which allow improving the formulations continuously. Due to their proven advantages and utilities, as well as their potential applications, it is essential to study these systems.
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微乳液体系:概论与应用领域
微乳液是由表面活性剂/助表面活性剂体系稳定的两相油-水体系,由表面活性剂分子的疏水或亲水部分自发自组装形成,在工业水平上因其独特的性能、改进工艺和降低成本而必不可少。它们在制药、化妆品和食品工业中的主要用途是改善药物的生物制药和药代动力学特性、皮肤渗透特性以及不同成分的稳定性和溶解度。它们可以通过相反转和相滴定等技术获得。它们的特点是采用不同的技术,可以获得有关动态特性、液滴大小、结构排列和取向、分子聚集和系统相互作用的信息,从而可以不断改进配方。由于它们已被证明的优势和实用程序,以及它们的潜在应用,研究这些系统是必不可少的。
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