An Artificial Neural Networks model for predicting patients’ mortality due to COVID-19 "CoviSurv2021"

Fatima Haddad, Saliha Ouadah, Lina Lefilef, M. A. Benbouras
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Abstract

Introduction. COVID-19 is the pandemic of the century with the unusual circumstances it generated. Subsequently, there has been medical and human scarcity of resources leading to the health system collapse, especially in third world countries. Objective. To support the white army in grasping the pandemic behavior, several studies have pointed to the existence of patient-related factors affecting COVID-19 patients’ mortality-risk. In the current study, Artificial Neural Network (ANN) has been employed to predict COVID-19 mortality. Material and methods. In particular, the modeling phase was done using a database of 684 samples collected from Mohamed Seddik Ben Yahia Hospital of Jijel, with antecedent diseases and blood biomarkers data of patients. Firstly, 18 parameters were selected in the input layer based on the literature recommendation and expert medical team consultation. Furthermore, the optimal inputs have been modeled using the ANN, and their performance was assessed through four performance measures (sensitivity, specificity, precision, and accuracy). Results. The comparative study proved the effectiveness of (18-12-2) model trained by Tansig transfer function, which displayed a higher performance in predicting COVID-19 mortality, compared to other models proposed in the literature. Afterward, the proposed optimal model was utilized to develop a GUI public interface by Matlab software. Conclusion. Finally, a reliable and easy-to-use graphical interface is generated in the current study dubbed “CoviSurv2021”. This latter will be very helpful for the medical staff to select priority patients who have upper urgency to be hospitalized, prioritize patients when the hospital is overcrowded, and gain time to provide the care needed.
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新型冠状病毒病死率预测的人工神经网络模型“CoviSurv2021”
介绍。2019冠状病毒病是本世纪的大流行,造成了不同寻常的情况。随后,医疗和人力资源短缺导致卫生系统崩溃,特别是在第三世界国家。目标。为了支持白军掌握大流行行为,多项研究指出,存在影响COVID-19患者死亡风险的患者相关因素。在本研究中,人工神经网络(ANN)被用于预测COVID-19死亡率。材料和方法。特别是,建模阶段使用了从吉耶勒Mohamed Seddik Ben Yahia医院收集的684个样本的数据库,其中包括患者的既往疾病和血液生物标志物数据。首先,根据文献推荐和专家医疗团队咨询,在输入层选择18个参数。此外,使用人工神经网络对最优输入进行建模,并通过四个性能指标(灵敏度、特异性、精度和准确性)对其性能进行评估。结果。对比研究证明了采用Tansig传递函数训练的(18-12-2)模型的有效性,与文献中提出的其他模型相比,该模型在预测COVID-19死亡率方面表现出更高的性能。随后,利用所提出的优化模型,利用Matlab软件开发了GUI公共界面。结论。最后,在当前的研究中生成了一个可靠且易于使用的图形界面,称为“CoviSurv2021”。后者将非常有助于医务人员选择最紧急的患者优先住院,在医院人满为患时优先考虑患者,并争取时间提供所需的护理。
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