Introduction. Malnutrition is one of main reasons for growth and puberty delay. Objective. To determine the prevalence of functional hypogonadotropic hypogonadism (FHH) from nutritional origin, and to study its clinical and biological characteristics. Population and methods. This retrospective study was conducted on 32 cases of FHH [secondary to Chronic Diseases + Constitutional Delay of Growth and Puberty (CDGP)], from a series of 125 patients evaluated for delayed puberty (DP) in the Endocrinology Department of the University Hospital Center of Constantine, between 2000 and 2010, and follow-up for at least 5 years. The diagnosis of malnutrition was clinical, according to the American Academy of Nutrition and Dietetics consensus. Each patient received a general check-up and a gonadotropic and thyrotropic hormonal assay. Other etiological explorations were clinically guided. FHH group was compared with isolated hypogonadotropic hypogonadism (IHH) group. Results. FHH constituted 26% of the series [21 boys/11 girls, (p<0.5)] vs 24% of IHH group. Secondary HHF represented 20% of cases in the series against 6% of CDGP. Malnutrition represented 27% of the series, 11% of which were directly responsible for delayed puberty (DP). Protein-energy undernutrition and iron deficiency anemia, due to inadequate intake, accounted for 62% of nutritional causes. There was a break in the growth curve in 97% of FHH vs 26% of IHH patients (p<0.001). FHH tripled the risk for developing growth retardation. Testicular volume of FHH group was 2.82±0.73 mL (2.69±0.4 mL in patients with malnutrition) vs 2.09±0.87 mL for IHH group (p<0.05). Conclusion. Despite therapeutic progress, DP in CD is common, representing a severity indicator, and poor control of CD. Prevention of FHH requires early detection, nutritional supplementation, and good control disease.
介绍。营养不良是发育和青春期延迟的主要原因之一。目标。从营养来源确定功能性促性腺功能减退症(FHH)的患病率，并研究其临床和生物学特征。人口和方法。本研究回顾性研究了32例FHH[继发于慢性疾病+发育和青春期的体质延迟(CDGP)]，来自康斯坦丁大学医院中心内分泌科2000年至2010年间评估为青春期延迟(DP)的125例患者，随访至少5年。根据美国营养与饮食学会的共识，对营养不良的诊断是临床的。每位患者接受了一般检查和促性腺激素和促甲状腺激素测定。其他病因探查均在临床指导下进行。FHH组与孤立性促性腺功能减退(IHH)组进行比较。结果。FHH组占26%[21名男孩/11名女孩，(p<0.5)]，而IHH组占24%。继发性HHF占该系列病例的20%，而CDGP占6%。营养不良占27%，其中11%直接导致青春期延迟(DP)。由于摄入不足导致的蛋白质能量营养不良和缺铁性贫血占营养原因的62%。97%的FHH患者和26%的IHH患者的生长曲线出现断裂(p<0.001)。FHH使发育迟缓的风险增加了两倍。FHH组睾丸体积为2.82±0.73 mL(营养不良组为2.69±0.4 mL)， IHH组为2.09±0.87 mL (p<0.05)。结论。尽管治疗取得了进展，但乳糜泻中DP很常见，这是一种严重程度指标，对乳糜泻控制不佳。预防FHH需要早期发现，补充营养，并对疾病进行良好控制。
{"title":"Delayed Puberty of nutritional origin : Analysis of a cases serie from an academic center of eastern Algeria","authors":"Khalida Boudaoud, M. Semrouni","doi":"10.30952/ns.12.1.1","DOIUrl":"https://doi.org/10.30952/ns.12.1.1","url":null,"abstract":"Introduction. Malnutrition is one of main reasons for growth and puberty delay. Objective. To determine the prevalence of functional hypogonadotropic hypogonadism (FHH) from nutritional origin, and to study its clinical and biological characteristics. Population and methods. This retrospective study was conducted on 32 cases of FHH [secondary to Chronic Diseases + Constitutional Delay of Growth and Puberty (CDGP)], from a series of 125 patients evaluated for delayed puberty (DP) in the Endocrinology Department of the University Hospital Center of Constantine, between 2000 and 2010, and follow-up for at least 5 years. The diagnosis of malnutrition was clinical, according to the American Academy of Nutrition and Dietetics consensus. Each patient received a general check-up and a gonadotropic and thyrotropic hormonal assay. Other etiological explorations were clinically guided. FHH group was compared with isolated hypogonadotropic hypogonadism (IHH) group. Results. FHH constituted 26% of the series [21 boys/11 girls, (p<0.5)] vs 24% of IHH group. Secondary HHF represented 20% of cases in the series against 6% of CDGP. Malnutrition represented 27% of the series, 11% of which were directly responsible for delayed puberty (DP). Protein-energy undernutrition and iron deficiency anemia, due to inadequate intake, accounted for 62% of nutritional causes. There was a break in the growth curve in 97% of FHH vs 26% of IHH patients (p<0.001). FHH tripled the risk for developing growth retardation. Testicular volume of FHH group was 2.82±0.73 mL (2.69±0.4 mL in patients with malnutrition) vs 2.09±0.87 mL for IHH group (p<0.05). Conclusion. Despite therapeutic progress, DP in CD is common, representing a severity indicator, and poor control of CD. Prevention of FHH requires early detection, nutritional supplementation, and good control disease.","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"254 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114292114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Bentaleb, I. Sersar, .Meriem Bencharif, Basma . Boukef, Nawel NAR.
Introduction. Milk and derived products occupy a special place in the consumption of the Algerian population. Objective. The objective of this study was to describe the milk and dairy productsplaceineastern Algeria adults population. Material and methods. A cross-sectional study by questionnaire was carried out on 750 subjects recruited in shopping centers, supermarkets and general food stores. The survey questionnaire gatheredgeneral characteristics, consumption of dairy products and their share in income, purchase of dairy products, and daily calcium intake of the subjects.Results were compared by Student, Khi2 and Anova tests. Results. The survey brought together 515 women and 235 men. Their average age was 31.9±7.7 years. The purchase share of dairy products was 37.6±16.6%, compared to other food products purchased at the level of the family home. Processed cheese was the most consumed product (93.7%), followed by sweet fermented fresh dairy products (87.9%). More than half of the subjects were influenced by relatives regarding the consumption of dairy products. Men purchase criteria for dairy products were in relation to taste, brand, price and nutritional value. The average calcium intake of the subjects (585.9±282.3 mg/day) was lower than the international recommendations. Conclusion. Milk and dairy products are widely consumed by all households, their consumption behavior is influenced by their close entourage, and taste is the most frequently selected as a purchasing criterion.[Introduction. Le lait et ses dérivés occupent une place particulière au sein de la consommation de la population algérienne. Objectif. L’objectif de cette étude était de décrire la place du lait et des dérivés chez une population d’adultes de l’est algérien. Matériel et méthodes. Une étude transversale par questionnaire a été réalisée sur 750 sujets recrutés au niveau de centres commerciaux, de supérettes et de magasins d’alimentation générale. Une fiche d’enquête a porté sur les carac-téristiques générales, la consommation des produits laitiers et leur part dans le revenu, l’achat des produits laitiers et l’apport calcique quotidien des sujets. La comparaison des résultats est effectuée par le test de Student, le Khi2 et l’Anova. Le seuil de signification retenu était de 0,05. Résultats. L’enquête a regroupé 515 femmes et 235 hommes. Leur moyenne d’âge était de 31,9±7,7 ans. La part de l’achat des produits laitiers était de 37,6±16,6%, par rapport aux autres produits alimentaires achetés au niveau du foyer familial. Le fromage fondu était le produit le plus consommé (93,7%), suivi des produits laitiers frais fermentés sucrés (87,9%). Plus de la moitié des sujets étaient influencés par les proches concernant la consommation des produits laitiers. Les critères d’achat des hommes pour les produits laitiers étaient par rapport au goût, la marque, le prix et la valeur nutritive. L’apport calcique moyen des sujets représentait 585,9±282,3 mg/jour et était inférieur aux
介绍。牛奶及其衍生产品在阿尔及利亚人口的消费中占有特殊的地位。目标。本研究的目的是描述阿尔及利亚东部成年人口中的牛奶和乳制品。材料和方法。采用问卷调查的方法，对在购物中心、超市和普通食品店招募的750名受试者进行横断面研究。调查问卷收集了调查对象的一般特征、乳制品消费量及其在收入中的占比、乳制品购买情况和每日钙摄入量。采用Student检验、Khi2检验和Anova检验对结果进行比较。结果。这项调查共有515名女性和235名男性参与。平均年龄31.9±7.7岁。与家庭层面购买的其他食品相比，乳制品的购买份额为37.6±16.6%。加工奶酪是消费最多的产品(93.7%)，其次是甜发酵新鲜乳制品(87.9%)。超过一半的研究对象在乳制品消费方面受到亲戚的影响。男性购买乳制品的标准与口味、品牌、价格和营养价值有关。受试者的平均钙摄入量(585.9±282.3 mg/d)低于国际推荐量。结论。牛奶及乳制品在所有家庭中广泛消费，其消费行为受到其亲密随从的影响，而口味是最常被选择作为购买标准的。我们的目标是让所有的人都能获得一个位置，特别是在所有的人都能获得一个位置。目的。目标是把成年的人当作成年的人当作成年的人当作成年的人当作成年的人。matsamriel et msamthodes。一份横向调查问卷和一份针对750名被调查对象的电子数据表:商业中心、超级电子数据表和营养杂志电子数据表。一份文件的格式为'enquête a port sur les carac- tanciesciques - csamnsamrales, la consommation des productlatiers et leur part dans le revenu, l 'achat des productlatiers et l 'apport calcique quotidien des sujets。用比较法比较了两种方法的有效性，用比较法比较了两种方法的有效性。Le seuil de meaning retenu日新月异。结果。L 'enquête a重组了515名女性和235名男性。Leur moyenne d ' 交换器(samt)， 31,9±7,7;La part de l ' achat des productlatiers samt, 37,6±16.6%;par rapport aux aures productalimentaires, achetsamt au niveau du foyer familial。Le froage fondu samtait Le product Le plus consommess (93,7%)， suvi des products latiers frais fermentsamaess samuess(87,9%)。另外，在与产品质量协调有关的过程中，受影响因素的影响也会影响到与产品质量协调有关的过程。《食品质量标准》，《食品质量标准》，《食品质量标准》，《食品质量标准》，《食品质量标准》，《营养价值标准》。L ' apapte钙质moyen des sureresamets585,9±282,3毫克/小时，以及国际上的建议。结论。[qh] [Le lait et les productlatiers] [qh] [qh] [qh] [qh] [qh] [qh] [qh] [qh] [qh] [qh]
{"title":"Milk and dairy products: between consumption, purchase criteria and calcium intake of adult population in eastern Algeria","authors":"M. Bentaleb, I. Sersar, .Meriem Bencharif, Basma . Boukef, Nawel NAR.","doi":"10.30952/ns.12.1.2","DOIUrl":"https://doi.org/10.30952/ns.12.1.2","url":null,"abstract":"Introduction. Milk and derived products occupy a special place in the consumption of the Algerian population. Objective. The objective of this study was to describe the milk and dairy productsplaceineastern Algeria adults population. Material and methods. A cross-sectional study by questionnaire was carried out on 750 subjects recruited in shopping centers, supermarkets and general food stores. The survey questionnaire gatheredgeneral characteristics, consumption of dairy products and their share in income, purchase of dairy products, and daily calcium intake of the subjects.Results were compared by Student, Khi2 and Anova tests. Results. The survey brought together 515 women and 235 men. Their average age was 31.9±7.7 years. The purchase share of dairy products was 37.6±16.6%, compared to other food products purchased at the level of the family home. Processed cheese was the most consumed product (93.7%), followed by sweet fermented fresh dairy products (87.9%). More than half of the subjects were influenced by relatives regarding the consumption of dairy products. Men purchase criteria for dairy products were in relation to taste, brand, price and nutritional value. The average calcium intake of the subjects (585.9±282.3 mg/day) was lower than the international recommendations. Conclusion. Milk and dairy products are widely consumed by all households, their consumption behavior is influenced by their close entourage, and taste is the most frequently selected as a purchasing criterion.[Introduction. Le lait et ses dérivés occupent une place particulière au sein de la consommation de la population algérienne. Objectif. L’objectif de cette étude était de décrire la place du lait et des dérivés chez une population d’adultes de l’est algérien. Matériel et méthodes. Une étude transversale par questionnaire a été réalisée sur 750 sujets recrutés au niveau de centres commerciaux, de supérettes et de magasins d’alimentation générale. Une fiche d’enquête a porté sur les carac-téristiques générales, la consommation des produits laitiers et leur part dans le revenu, l’achat des produits laitiers et l’apport calcique quotidien des sujets. La comparaison des résultats est effectuée par le test de Student, le Khi2 et l’Anova. Le seuil de signification retenu était de 0,05. Résultats. L’enquête a regroupé 515 femmes et 235 hommes. Leur moyenne d’âge était de 31,9±7,7 ans. La part de l’achat des produits laitiers était de 37,6±16,6%, par rapport aux autres produits alimentaires achetés au niveau du foyer familial. Le fromage fondu était le produit le plus consommé (93,7%), suivi des produits laitiers frais fermentés sucrés (87,9%). Plus de la moitié des sujets étaient influencés par les proches concernant la consommation des produits laitiers. Les critères d’achat des hommes pour les produits laitiers étaient par rapport au goût, la marque, le prix et la valeur nutritive. L’apport calcique moyen des sujets représentait 585,9±282,3 mg/jour et était inférieur aux","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132784478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Moufida Djalleb, A. Dehimi, MT Saadi, Zoheir Laib, A. Hamada, B. Bioud
Introduction. Pediatric asthma is predominantly atopic, but no data are found on atopy in obese asthmatic child in the literature. In addition, the increased obesity rates, sensitization to airborne allergens are a risk factor for asthma. Objective. To determine whether elevation of body mass index (BMI) was associated with asthma severity or with sensitization to inhalation allergens in adolescents in the wilaya of Constantine. Material and methods. This was a prospective, descriptive and cross-sectional study, carried out during the 2017-2018 school year, on 104 asthmatic adolescents, aged between 13 and 14, in schools in Constantine. The weight status of the patients was assessed using the 2012 thresholds of the International Obesity Task Force (IOTF), and a BMI ≥ 25 kg/m2 defined overweight or obesity. Asthmatics obese and non-obese groups were compared for the prevalence of severe asthma and sensitization using the Chi-square test, at the 95% confidence interval. Results. Twenty-five per cent of asthmatics were overweight or obese with an average BMI of 28,20±3,80. Asthma symptoms were persistent in 66%, and uncontrolled in 40% of cases. Almost 70% of the population were atopic, and 50% were poly-sensitized. Sensitization occurred in both groups with a significant positive ratio (p=0.03). No association was observed between obesity and prevalence of severe asthma (p=0.5), or poly-sensitizations. Conclusion. The quarter of adolescents is overweight or obese, and tends to present an atopy. However, no positive association is found between obesity and prevalence of severe asthma symptoms. Further prospective studies are needed for a better understanding of this obese asthmatics group.[Introduction. L’asthme pédiatrique est majoritairement atopique, mais aucune donnée n’existe sur l’atopie de l’enfant asthmatique obèse dans la littérature. En outre, l’élévation du taux d’obésité, la sensibilisation aux pneumallergènes sont un facteur de risque pour l’asthme. Objectif. Déterminer si l’élévation de l’indice de masse corporelle (IMC) est associée à la sévérité de l’asthme ou à la sensibilisation aux pneumallergènes, chez des adolescents asthmatiques dans la wilaya de Constantine. Matériel et méthodes. Une étude prospective, descriptive et transversale est réalisée durant l’année scolaire 2017-2018, et a porté sur 104 adolescents asthmatiques, âgés entre 13 et 14 ans, au sein des établissements scolaires de Constantine. Le statut pondéral des malades a été évalué en utilisant les seuils de l’International Obesity Task Force (IOTF), avec un indice de masse corporelle (IMC) ≥ 25 kg/m² définissant le surpoids ou l’obésité. Des groupes d’asthmatiques obèses et non obèses ont été comparés afin de noter la prévalence de l’asthme sévère et la sensibilisation en utilisant le test de Chi-deux à l’intervalle de confiance de 95 %. Résultats. Un quart des asthmatiques étaient en surpoids ou obèses avec un IMC moyen de 28,20±3,80. Les symptômes d’asthme étaient
{"title":"Relationship between asthma, atopy and obesity in adolescents living in the Wilaya of Constantine, Algeria","authors":"Moufida Djalleb, A. Dehimi, MT Saadi, Zoheir Laib, A. Hamada, B. Bioud","doi":"10.30952/ns.12.1.3","DOIUrl":"https://doi.org/10.30952/ns.12.1.3","url":null,"abstract":"Introduction. Pediatric asthma is predominantly atopic, but no data are found on atopy in obese asthmatic child in the literature. In addition, the increased obesity rates, sensitization to airborne allergens are a risk factor for asthma. Objective. To determine whether elevation of body mass index (BMI) was associated with asthma severity or with sensitization to inhalation allergens in adolescents in the wilaya of Constantine. Material and methods. This was a prospective, descriptive and cross-sectional study, carried out during the 2017-2018 school year, on 104 asthmatic adolescents, aged between 13 and 14, in schools in Constantine. The weight status of the patients was assessed using the 2012 thresholds of the International Obesity Task Force (IOTF), and a BMI ≥ 25 kg/m2 defined overweight or obesity. Asthmatics obese and non-obese groups were compared for the prevalence of severe asthma and sensitization using the Chi-square test, at the 95% confidence interval. Results. Twenty-five per cent of asthmatics were overweight or obese with an average BMI of 28,20±3,80. Asthma symptoms were persistent in 66%, and uncontrolled in 40% of cases. Almost 70% of the population were atopic, and 50% were poly-sensitized. Sensitization occurred in both groups with a significant positive ratio (p=0.03). No association was observed between obesity and prevalence of severe asthma (p=0.5), or poly-sensitizations. Conclusion. The quarter of adolescents is overweight or obese, and tends to present an atopy. However, no positive association is found between obesity and prevalence of severe asthma symptoms. Further prospective studies are needed for a better understanding of this obese asthmatics group.[Introduction. L’asthme pédiatrique est majoritairement atopique, mais aucune donnée n’existe sur l’atopie de l’enfant asthmatique obèse dans la littérature. En outre, l’élévation du taux d’obésité, la sensibilisation aux pneumallergènes sont un facteur de risque pour l’asthme. Objectif. Déterminer si l’élévation de l’indice de masse corporelle (IMC) est associée à la sévérité de l’asthme ou à la sensibilisation aux pneumallergènes, chez des adolescents asthmatiques dans la wilaya de Constantine. Matériel et méthodes. Une étude prospective, descriptive et transversale est réalisée durant l’année scolaire 2017-2018, et a porté sur 104 adolescents asthmatiques, âgés entre 13 et 14 ans, au sein des établissements scolaires de Constantine. Le statut pondéral des malades a été évalué en utilisant les seuils de l’International Obesity Task Force (IOTF), avec un indice de masse corporelle (IMC) ≥ 25 kg/m² définissant le surpoids ou l’obésité. Des groupes d’asthmatiques obèses et non obèses ont été comparés afin de noter la prévalence de l’asthme sévère et la sensibilisation en utilisant le test de Chi-deux à l’intervalle de confiance de 95 %. Résultats. Un quart des asthmatiques étaient en surpoids ou obèses avec un IMC moyen de 28,20±3,80. Les symptômes d’asthme étaient ","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126644979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Moringa oleifera L. is a medicinal plant reported to have thera- peutic potency. Objective. The aim of this work was to study the effect of M. oleifera extract, at a dose of 800 mg/kg, on induced hypercholesterolemia in mice. Material and methods. Male mice (n=30) were used and randomly divided into five equal groups (n=5). Triton X-100 (100mg/kg body weight, i.p.) was administered to induce hypercholesterolemia. Then, oral treatment of Atorvastatin or methanolic extract of M. oleifera leaves (MEMOL) was given daily to treated groups for 7 days. Lipid profile was determined at the end of the treatment. Results. Results showed that mice group treated with MEMOL showed reduced total cholesterol (TC) (136.5 mg/dL), and low density lipoproteins cholesterol (LDL-C) (60.65 mg/dL) levels, when compared to hypercholesterolemic group (242.13 and 168.9 mg/dL for TC and LDL-C, respectively). High density lipoproteins cholesterol (HDL-C) value of treated mice by MEMOL and atorvastatine was comparable and higher than that of other groups. Significant increase in HDL-C level was observed in mice treated with MEMOL. Atherogenic index was signi-fycantly lower (P<0.05) in MEMOL treated hypercholesterolemic mice than hypercho-lesterolemic mice. Conclusion. Results indicate that M. oleifera has anti-hypercholesterolemic effect, justifying its use in ethnomedicine. [Introduction. Moringa oleifera L. est une plante médicinale ayant un pouvoir thérapeutique sur plusieurs pathologies. Objectif. Le but de ce travail est d’étudier l’effet de cette plante sur une hypercholestérolémie induite chez des souris à une dose de 800 mg/kg d’extrait de poudre de feuilles de M. oleifera. Matériel et méthodes. Trente souris mâles ont été utilisées et réparties au hasard en cinq groupes égaux (n = 5). Le Triton X-100 (100 mg/kg de poids corporel, i.p.) a été administré pour induire une hypercholestérolémie. Par la suite, un traitement oral d'Atorvastatine ou d'un extrait méthanolique de feuilles de M. oleifera (MEMOL) a été administré quotidiennement aux groupes traités pendant 7 jours. Le profil lipidique a été déterminé à la fin du traitement. Résultats. Le groupe de souris traitées avec MEMOL présentait une réduction des taux de cholestérol total (CT) (136,5mg/dL) et de cholesterol des lipoprotéines de faible densité (C-LDL) (60,65mg/dL), comparé au groupe hypercholestérolémique (242,13 et 168,9mg/dL pour CT et C-LDL, respectivement). La valeur du cholestérol des lipoprotéines de haute densité (C-HDL), chez les souris traitées soit avec MEMOL, soit avec atorvastatine, était comparable et supérieure à celle des souris des autres groupes. Une augmentation significative du taux de C-HDL est observée chez les souris traitées avec MEMOL. L'indice d’athérogénicité s'est avéré significativement plus faible (P<0,05), chez les souris hypercholestérolémiques traitées avec MEMOL, par rapport aux souris hypercholestérolémiques. Conclusion. Les résultats de cette étude indiquent
介绍。辣木(Moringa oleifera L.)是一种据报道具有治疗作用的药用植物。目标。本研究旨在研究油橄榄提取物在800 mg/kg剂量下对小鼠高胆固醇血症的影响。材料和方法。选取雄性小鼠30只，随机分为5组(n=5)。给予Triton X-100 (100mg/kg体重，i.p)诱导高胆固醇血症。然后，给药组每天口服阿托伐他汀或油葵叶甲醇提取物(MEMOL)，连续7 d。在治疗结束时测定血脂。结果。结果显示，与高胆固醇血症组(TC和LDL-C分别为242.13和168.9 mg/dL)相比，MEMOL组小鼠总胆固醇(TC) (136.5 mg/dL)和低密度脂蛋白胆固醇(LDL-C) (60.65 mg/dL)水平降低。MEMOL和阿托伐他汀治疗小鼠的高密度脂蛋白胆固醇(HDL-C)值与其他各组相当且高于其他各组。小鼠经MEMOL处理后，HDL-C水平明显升高。MEMOL处理的高胆固醇血症小鼠的动脉粥样硬化指数明显低于高胆固醇血症小鼠(P<0.05)。结论。结果表明，油桐具有抗高胆固醇作用，证明其在民族医药中的应用是合理的。(介绍。辣木(Moringa oleifera L.)是一种植物，它与其他植物的病变有关。目的。但是，我们的研究表明，在高胆固醇的情况下，我们的研究表明，在高胆固醇的情况下，我们的研究表明，在高胆固醇的情况下，我们的研究表明，在高胆固醇的情况下，我们的研究表明，在高胆固醇的情况下，我们的研究表明，在高胆固醇的情况下，我们的研究表明:matsamriel et msamthodes。Triton X-100 (100 mg/kg de poids corporel, i.p)是一种具有高胆固醇含量的(5))。一组，一组，一组，一组，一组，一组，一组，一组，一组，一组，一组，一组，一组，一组，一组，待7个小时。Le profile lipidique a samuest dsamuter la fin du traitement。结果。勒德集团对牛群贩卖用MEMOL presentait减少一个des taux de胆固醇总(CT)(136年5 mg / dL) et de des脂蛋白胆固醇de faible三硝基甲苯炸药(C-LDL)(60、65 mg / dL),比较非盟groupe hypercholesterolemique(168年242年,13等9 mg / dL倒CT C-LDL, respectivement)。高密度脂蛋白胆固醇与高密度脂蛋白(C-HDL)的比值，高密度脂蛋白与高密度脂蛋白的比值，高密度脂蛋白与高密度脂蛋白的比值，高密度脂蛋白与高密度脂蛋白的比值，高密度脂蛋白与高密度脂蛋白的比值，高密度脂蛋白与高密度脂蛋白的比值，高密度脂蛋白与高密度脂蛋白的比值。一项显著的C-HDL升高的研究表明，与MEMOL相比，C-HDL升高的幅度更小。L' indici d ' athathrosamicnicicicsys 'est avavacri -显著性+不显著性(P< 0.05)， s' indici d ' athathrosamicicsade -高胆固醇的samicicsade -高胆固醇的samicicsade -高胆固醇的samicsade -高胆固醇的samicsade -高胆固醇的samicsade -高胆固醇的samicsade -高胆固醇的samicsade -高胆固醇的samicsade -高胆固醇。结论。[3] [M. oleifera]是一种有效的抗高胆固醇的samo，合理的使用与传统的samo相比。]
{"title":"Anticholesterolemic activity of Moringa oleifera leaves methanolic extract in Triton X-100 induced hypercholesterolemic mice","authors":"Yassamine R. Saidi, A. Doumandji","doi":"10.30952/ns.12.1.4","DOIUrl":"https://doi.org/10.30952/ns.12.1.4","url":null,"abstract":"Introduction. Moringa oleifera L. is a medicinal plant reported to have thera- peutic potency. Objective. The aim of this work was to study the effect of M. oleifera extract, at a dose of 800 mg/kg, on induced hypercholesterolemia in mice. Material and methods. Male mice (n=30) were used and randomly divided into five equal groups (n=5). Triton X-100 (100mg/kg body weight, i.p.) was administered to induce hypercholesterolemia. Then, oral treatment of Atorvastatin or methanolic extract of M. oleifera leaves (MEMOL) was given daily to treated groups for 7 days. Lipid profile was determined at the end of the treatment. Results. Results showed that mice group treated with MEMOL showed reduced total cholesterol (TC) (136.5 mg/dL), and low density lipoproteins cholesterol (LDL-C) (60.65 mg/dL) levels, when compared to hypercholesterolemic group (242.13 and 168.9 mg/dL for TC and LDL-C, respectively). High density lipoproteins cholesterol (HDL-C) value of treated mice by MEMOL and atorvastatine was comparable and higher than that of other groups. Significant increase in HDL-C level was observed in mice treated with MEMOL. Atherogenic index was signi-fycantly lower (P<0.05) in MEMOL treated hypercholesterolemic mice than hypercho-lesterolemic mice. Conclusion. Results indicate that M. oleifera has anti-hypercholesterolemic effect, justifying its use in ethnomedicine. [Introduction. Moringa oleifera L. est une plante médicinale ayant un pouvoir thérapeutique sur plusieurs pathologies. Objectif. Le but de ce travail est d’étudier l’effet de cette plante sur une hypercholestérolémie induite chez des souris à une dose de 800 mg/kg d’extrait de poudre de feuilles de M. oleifera. Matériel et méthodes. Trente souris mâles ont été utilisées et réparties au hasard en cinq groupes égaux (n = 5). Le Triton X-100 (100 mg/kg de poids corporel, i.p.) a été administré pour induire une hypercholestérolémie. Par la suite, un traitement oral d'Atorvastatine ou d'un extrait méthanolique de feuilles de M. oleifera (MEMOL) a été administré quotidiennement aux groupes traités pendant 7 jours. Le profil lipidique a été déterminé à la fin du traitement. Résultats. Le groupe de souris traitées avec MEMOL présentait une réduction des taux de cholestérol total (CT) (136,5mg/dL) et de cholesterol des lipoprotéines de faible densité (C-LDL) (60,65mg/dL), comparé au groupe hypercholestérolémique (242,13 et 168,9mg/dL pour CT et C-LDL, respectivement). La valeur du cholestérol des lipoprotéines de haute densité (C-HDL), chez les souris traitées soit avec MEMOL, soit avec atorvastatine, était comparable et supérieure à celle des souris des autres groupes. Une augmentation significative du taux de C-HDL est observée chez les souris traitées avec MEMOL. L'indice d’athérogénicité s'est avéré significativement plus faible (P<0,05), chez les souris hypercholestérolémiques traitées avec MEMOL, par rapport aux souris hypercholestérolémiques. Conclusion. Les résultats de cette étude indiquent ","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131207595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Laoufi, K. Boudjema, S. Lefkir, N. Benhabyles, O. Bouchenak, K. Yahiaoui
Abstract Introduction. The natural plant resources are products with high added value, used in various fields for the manufacture of a wide variety of products. Objective. The purpose of this study was the physicochemical and chromatographic characterization of Ziziphus jujuba seeds vegetable oil, and the evaluation of their antioxidant and anti-inflammatory activity. Material and methods. Seeds oil extraction was done by soxhlet. Fatty acid content was determined by gas chromatography (GPC). Organoleptic and physicochemical characteristics were determined, and antioxidant activity was evalua-ted by diphenyl-picryl-hydrazyl (DPPH) test and -carotene bleaching. Anti-inflam-matory activity was essayed using carrageenan-induced plantar edema model in mice. Results. Extracted seeds oil had an extraction yield of 3.4%. GPC characterization sho-wed the presence of 12 fatty acids with a predominance of oleic acid (47.02%), and linoleic acid (37.40%). Physicochemical parameters of Ziziphus jujuba seeds oil showed an acidity of 2.05%, a saponification value of 198.17 mg KOH/mL, and refractive index of 1.471±0.00. This oil expressed a significant antiradical activity for the DPPH test, and low for that of β-carotene. In vivo study of edema induction in mice showed that oil had a maximum effective effect in inhibiting oedema (55.89±0.03%), at the first hour, compared to Diclofenac (19.88±0.12%), at the same hour. Conclusion. These results highlight the fatty acids richness of Ziziphus jujuba seeds oil with antioxidant and anti-inflammatory effects. These properties make it possible to predict its use in biotech-nology and cosmetology. [Introduction. Les ressources naturelles végétales sont des produits à forte valeur ajoutée, utilisés dans divers domaines pour la fabrication d’une large variété de produits. Objectif. Le présent travail a pour but la caractérisation physico-chimique et chromatographique de l’huile végétale des graines de Ziziphus jujuba Mill., et l’évaluation de leur activité antioxydante et anti-inflammatoire. Matériel et méthodes. L’huile des graines extraite par soxhlet est caractérisée sur le plan organoleptique et physicochimique. La teneur en acides gras est déterminée par une analyse chromato-graphique en phase gazeuse (CPG). L’activité antioxydante est évaluée par le test diphe-nyl-picryl-hydrazyl (DPPH) et le test de blanchiment. L’activité anti-inflammatoire est déterminée à l’aide du modèle de l’œdème plantaire induit chez la souris par la carra-génine. Résultats. L’huile présente un rendement d’extraction de 3,14%. La caracté-risation par la CPG montre la présence de 12 acides gras avec une prédominance de l’acide oléique (47,02%) et l’acide linoléique (37,40%). Les paramètres physico-chimi-ques ont montré une acidité de 2,05%, un indice de saponification de 198,17mg KOH/mL, un indice de réfraction de 1,471±0,00. L’huile végétale testée exprime une activité anti-radicalaire importante pour le test de DPPH et forte pour celui de
摘要介绍。天然植物资源是具有高附加值的产品，应用于各个领域，用于制造各种产品。目标。对酸枣籽植物油进行理化、色谱表征，并对其抗氧化、抗炎活性进行评价。材料和方法。用索氏法提取种子油。采用气相色谱法测定脂肪酸含量。测定了其感官和理化特性，并通过DPPH试验和-胡萝卜素漂白法评价了其抗氧化活性。采用卡拉胶诱导小鼠足底水肿模型，测定其抗炎活性。结果。提取籽油得率为3.4%。GPC表征表明，共存在12种脂肪酸，其中以油酸(47.02%)和亚油酸(37.40%)为主。理化参数表明，酸枣籽油酸度为2.05%，皂化值为198.17 mg KOH/mL，折射率为1.471±0.00。这种油在DPPH测试中表现出显著的抗自由基活性，而在β-胡萝卜素测试中表现出较低的抗自由基活性。小鼠诱导水肿的体内实验表明，精油在第1小时的抑制水肿效果最大(55.89±0.03%)，而双氯芬酸在同一小时的抑制效果为19.88±0.12%。结论。结果表明，酸枣籽油脂肪酸丰富，具有抗氧化和抗炎作用。这些特性使得预测其在生物技术和美容方面的应用成为可能。(介绍。低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源、低资源。目的。在Ziziphus枣树磨粒时，用物理化学和色谱法测定了Ziziphus枣树磨粒。抗氧化抗炎药。matsamriel et msamthodes。在机械、感官和物理化学方面，我们都有自己的想法。用色谱-液相色谱法(CPG)分析酸盐的含量。抗氧化活性测试、抗氧化活性测试、抗氧化活性测试、抗氧化活性测试、抗氧化活性测试和抗氧化活性测试。L ' activit消炎药est danci.9159.com - danci.9158.com - danci.9158.com - danci.9158.com - danci.9158.com。结果。L 'huile prassente unrenement d 'extraction为3.14%。La caractacry - risationparla CPG montre La pracentsence de 12个acides，平均为1个pracentdominance de l 'acide olsamique(47.02%)和l 'acide linolsamique(37.40%)。实验结果表明:1 .酸碱浓度为2 05%，脱皂化浓度为198,17mg KOH/mL，脱皂化浓度为1471±0000。与此同时，vcv - 3cv - 3cv - 3cv - 3cv - 3cv - 3cv - 3cv - 3cv - 3cv。L ' induction d ' œdème chez les source是一种监测效果，效果最大化的方法，而L ' inhibition de L ' œdème①①premiire①①，par rapport au diclof * * *①①même①。结论。红枣具有抗氧化和抗炎的功效。红枣具有抗氧化和抗炎的功效。在生物技术和宇宙的应用中，这些固有的薪金和薪金是相互渗透的。
{"title":"Valorization and biological effect of Zizuphus jujuba Mill. vegetable oil","authors":"R. Laoufi, K. Boudjema, S. Lefkir, N. Benhabyles, O. Bouchenak, K. Yahiaoui","doi":"10.30952/ns.12.1.5","DOIUrl":"https://doi.org/10.30952/ns.12.1.5","url":null,"abstract":"Abstract Introduction. The natural plant resources are products with high added value, used in various fields for the manufacture of a wide variety of products. Objective. The purpose of this study was the physicochemical and chromatographic characterization of Ziziphus jujuba seeds vegetable oil, and the evaluation of their antioxidant and anti-inflammatory activity. Material and methods. Seeds oil extraction was done by soxhlet. Fatty acid content was determined by gas chromatography (GPC). Organoleptic and physicochemical characteristics were determined, and antioxidant activity was evalua-ted by diphenyl-picryl-hydrazyl (DPPH) test and -carotene bleaching. Anti-inflam-matory activity was essayed using carrageenan-induced plantar edema model in mice. Results. Extracted seeds oil had an extraction yield of 3.4%. GPC characterization sho-wed the presence of 12 fatty acids with a predominance of oleic acid (47.02%), and linoleic acid (37.40%). Physicochemical parameters of Ziziphus jujuba seeds oil showed an acidity of 2.05%, a saponification value of 198.17 mg KOH/mL, and refractive index of 1.471±0.00. This oil expressed a significant antiradical activity for the DPPH test, and low for that of β-carotene. In vivo study of edema induction in mice showed that oil had a maximum effective effect in inhibiting oedema (55.89±0.03%), at the first hour, compared to Diclofenac (19.88±0.12%), at the same hour. Conclusion. These results highlight the fatty acids richness of Ziziphus jujuba seeds oil with antioxidant and anti-inflammatory effects. These properties make it possible to predict its use in biotech-nology and cosmetology. [Introduction. Les ressources naturelles végétales sont des produits à forte valeur ajoutée, utilisés dans divers domaines pour la fabrication d’une large variété de produits. Objectif. Le présent travail a pour but la caractérisation physico-chimique et chromatographique de l’huile végétale des graines de Ziziphus jujuba Mill., et l’évaluation de leur activité antioxydante et anti-inflammatoire. Matériel et méthodes. L’huile des graines extraite par soxhlet est caractérisée sur le plan organoleptique et physicochimique. La teneur en acides gras est déterminée par une analyse chromato-graphique en phase gazeuse (CPG). L’activité antioxydante est évaluée par le test diphe-nyl-picryl-hydrazyl (DPPH) et le test de blanchiment. L’activité anti-inflammatoire est déterminée à l’aide du modèle de l’œdème plantaire induit chez la souris par la carra-génine. Résultats. L’huile présente un rendement d’extraction de 3,14%. La caracté-risation par la CPG montre la présence de 12 acides gras avec une prédominance de l’acide oléique (47,02%) et l’acide linoléique (37,40%). Les paramètres physico-chimi-ques ont montré une acidité de 2,05%, un indice de saponification de 198,17mg KOH/mL, un indice de réfraction de 1,471±0,00. L’huile végétale testée exprime une activité anti-radicalaire importante pour le test de DPPH et forte pour celui de ","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115281226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Djabir Daddiouaissa, A. Azura, Hassen Houache, N. Bouras, S. Boukraa
Introduction. The adverse effects awareness of the chemicals misuse applied in food production is continuously increasing among consumers. In parallel, there is a rising trend in purchasing organically grown foods. Objective. This study aimed to evaluate Algerian consumers awareness and attitudes toward organic food products, and identify factors influencing their decision to purchase these organically grown foods. Material and methods. Survey data were obtained from 429 consumers via a 32-scale structured questionnaire, and evaluated with SPSS 25.0 and AMOS 25.0 using confirmatory factor analysis (CFA), and structural equation modeling (SEM). Hypotheses were verified by evaluating data via SEM, where mediating variables were attitude and purchasing intention. Results. The main reasons for Algerian consumers to consume organic food were health concerns, followed by environmentally friendly, pesticide-free, and better taste. Moreover, three factors namely health consciousness, subjective norms, and perception of availability were revealed to influence consumer buying behaviour towards organic food products. This occurred either by a direct effect such as availability perception or by a partial mediation of purchase intention, like subjective norms or by full mediating of attitude toward organic food, and purchase intention as the health consciousness factor did. Conclusion. The present study can guide and help agricultural policymakers to promote shifting to organic farming, which would benefit the ecosystem and human wellbeing. Furthermore, the report provides clear guidance for industry professionals who need to develop successful marketing strategies by addressing the main motivators of organic food consumption.
{"title":"Consumer awareness and actual buying behaviour of organic food in Algeria","authors":"Djabir Daddiouaissa, A. Azura, Hassen Houache, N. Bouras, S. Boukraa","doi":"10.30952/ns.11.1.2","DOIUrl":"https://doi.org/10.30952/ns.11.1.2","url":null,"abstract":"Introduction. The adverse effects awareness of the chemicals misuse applied in food production is continuously increasing among consumers. In parallel, there is a rising trend in purchasing organically grown foods. Objective. This study aimed to evaluate Algerian consumers awareness and attitudes toward organic food products, and identify factors influencing their decision to purchase these organically grown foods. Material and methods. Survey data were obtained from 429 consumers via a 32-scale structured questionnaire, and evaluated with SPSS 25.0 and AMOS 25.0 using confirmatory factor analysis (CFA), and structural equation modeling (SEM). Hypotheses were verified by evaluating data via SEM, where mediating variables were attitude and purchasing intention. Results. The main reasons for Algerian consumers to consume organic food were health concerns, followed by environmentally friendly, pesticide-free, and better taste. Moreover, three factors namely health consciousness, subjective norms, and perception of availability were revealed to influence consumer buying behaviour towards organic food products. This occurred either by a direct effect such as availability perception or by a partial mediation of purchase intention, like subjective norms or by full mediating of attitude toward organic food, and purchase intention as the health consciousness factor did. Conclusion. The present study can guide and help agricultural policymakers to promote shifting to organic farming, which would benefit the ecosystem and human wellbeing. Furthermore, the report provides clear guidance for industry professionals who need to develop successful marketing strategies by addressing the main motivators of organic food consumption.","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127409003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Pelargonium graveolens is a well-known ethno-medicinal plant used in traditional medicine, whereas Pelargonium zonale has not been investigated thoroughly. Objective. This study was designed to quantify phenolic compounds in extracts of Pelargonium graveolens and Pelargonium zonale, evaluate their antioxidant activities, establish a method for assaying phenolic compounds by HPLC-DAD, and determine the antimicrobial activity of these extracts. Material and methods. Aerial parts polyphenols were extracted with solvents of different polarities. Total content of polyphenols, flavonoids, and condensed tannins were determined. Antioxidant activity was assessed by measuring free radical scavenging activity of 2,2-diphenyl-2-picrylhydrazyl (DPPH). Agilent C18 with a linear gradient elution program was performed for chromatographic separation, and disk diffusion method was used to determine antimicrobial activity. Results. Total polyphenols content ranged from 159.4 to 164.2 mg GAE/g, and that of total flavonoids from 26.92 to 63.68 mg QE/g. DPPH values of ethanol extracts reached IC50 = 91.84±0.1 μg/mL. HPLC method permitted to analyze and separate twelve phenolic compounds (Acacetin, apigenin, myrecitin, quercetin, catechin, naringin, hesperetin, galengine, flavone, tannic acid, vanillic acid, and α-tocopherol). Extracts showed moderate to strong antimicrobial activity against five strains withminimum inhibitory concentration (MIC) ranging from 0.46 to 3.9 mg/mL. Conclusion. These results confirm richness of extracts by phenolic compounds, and are strongly correlated with DPPH values. In addition, the applied method is precise, and allows simultaneous determination of 12 phenolic compounds.
{"title":"henol analysis by HPLC-DAD, and antimicrobial and antioxidant activities of two species extracts of Pelargonium: P. graveolens and P. zonale","authors":"A. Harzallah, K. Hachama, ,Abdelkader Khadraoui","doi":"10.30952/ns.11.1.5","DOIUrl":"https://doi.org/10.30952/ns.11.1.5","url":null,"abstract":"Introduction. Pelargonium graveolens is a well-known ethno-medicinal plant used in traditional medicine, whereas Pelargonium zonale has not been investigated thoroughly. Objective. This study was designed to quantify phenolic compounds in extracts of Pelargonium graveolens and Pelargonium zonale, evaluate their antioxidant activities, establish a method for assaying phenolic compounds by HPLC-DAD, and determine the antimicrobial activity of these extracts. Material and methods. Aerial parts polyphenols were extracted with solvents of different polarities. Total content of polyphenols, flavonoids, and condensed tannins were determined. Antioxidant activity was assessed by measuring free radical scavenging activity of 2,2-diphenyl-2-picrylhydrazyl (DPPH). Agilent C18 with a linear gradient elution program was performed for chromatographic separation, and disk diffusion method was used to determine antimicrobial activity. Results. Total polyphenols content ranged from 159.4 to 164.2 mg GAE/g, and that of total flavonoids from 26.92 to 63.68 mg QE/g. DPPH values of ethanol extracts reached IC50 = 91.84±0.1 μg/mL. HPLC method permitted to analyze and separate twelve phenolic compounds (Acacetin, apigenin, myrecitin, quercetin, catechin, naringin, hesperetin, galengine, flavone, tannic acid, vanillic acid, and α-tocopherol). Extracts showed moderate to strong antimicrobial activity against five strains withminimum inhibitory concentration (MIC) ranging from 0.46 to 3.9 mg/mL. Conclusion. These results confirm richness of extracts by phenolic compounds, and are strongly correlated with DPPH values. In addition, the applied method is precise, and allows simultaneous determination of 12 phenolic compounds.","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126364053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amina Bayazid, Amel Youcef, Yasmina Mahsar, Aicha Dous
Introduction. From the onset of the COVID-19 pandemic, calls for taking certain dietary supplements were launched to prevent or treat this disease. Given the novelty of the subject, there are few national or international data on their consumption by the general public. Objective. To explore changes in dietary supplement consumption before and during this pandemic. Population and methods. A cross-sectional study was carried out online using a questionnaire, among 1000 Algerian citizens. Results. The prevalence of dietary supplement consumption doubled during this crisis (29.4% before vs 63.4% after the pandemic). Overall, a significant increase was noted in vitamins minerals, trace elements, and plant supplements intake, and was respectively 24.7%, 18.4% and 9.2% before vs 58.0%, 50.0% and 26.0% during the pandemic. The major changes concerned supplements based on vitamins (Vit.) C and D, zinc, magnesium, selenium, cloves, ginger, turmeric, liquorice, and omega-3. Conclusion. Although the scientific debate about the health impact of dietary supplements is endless, their consumption continues to increase. The biggest challenge now is to standardize their indications.
{"title":"Impact of COVID-19 pandemic on dietary supplements consumption in Algeria","authors":"Amina Bayazid, Amel Youcef, Yasmina Mahsar, Aicha Dous","doi":"10.30952/ns.11.1.3","DOIUrl":"https://doi.org/10.30952/ns.11.1.3","url":null,"abstract":"Introduction. From the onset of the COVID-19 pandemic, calls for taking certain dietary supplements were launched to prevent or treat this disease. Given the novelty of the subject, there are few national or international data on their consumption by the general public. Objective. To explore changes in dietary supplement consumption before and during this pandemic. Population and methods. A cross-sectional study was carried out online using a questionnaire, among 1000 Algerian citizens. Results. The prevalence of dietary supplement consumption doubled during this crisis (29.4% before vs 63.4% after the pandemic). Overall, a significant increase was noted in vitamins minerals, trace elements, and plant supplements intake, and was respectively 24.7%, 18.4% and 9.2% before vs 58.0%, 50.0% and 26.0% during the pandemic. The major changes concerned supplements based on vitamins (Vit.) C and D, zinc, magnesium, selenium, cloves, ginger, turmeric, liquorice, and omega-3. Conclusion. Although the scientific debate about the health impact of dietary supplements is endless, their consumption continues to increase. The biggest challenge now is to standardize their indications.","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124209504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatima Haddad, Saliha Ouadah, Lina Lefilef, M. A. Benbouras
Introduction. COVID-19 is the pandemic of the century with the unusual circumstances it generated. Subsequently, there has been medical and human scarcity of resources leading to the health system collapse, especially in third world countries. Objective. To support the white army in grasping the pandemic behavior, several studies have pointed to the existence of patient-related factors affecting COVID-19 patients’ mortality-risk. In the current study, Artificial Neural Network (ANN) has been employed to predict COVID-19 mortality. Material and methods. In particular, the modeling phase was done using a database of 684 samples collected from Mohamed Seddik Ben Yahia Hospital of Jijel, with antecedent diseases and blood biomarkers data of patients. Firstly, 18 parameters were selected in the input layer based on the literature recommendation and expert medical team consultation. Furthermore, the optimal inputs have been modeled using the ANN, and their performance was assessed through four performance measures (sensitivity, specificity, precision, and accuracy). Results. The comparative study proved the effectiveness of (18-12-2) model trained by Tansig transfer function, which displayed a higher performance in predicting COVID-19 mortality, compared to other models proposed in the literature. Afterward, the proposed optimal model was utilized to develop a GUI public interface by Matlab software. Conclusion. Finally, a reliable and easy-to-use graphical interface is generated in the current study dubbed “CoviSurv2021”. This latter will be very helpful for the medical staff to select priority patients who have upper urgency to be hospitalized, prioritize patients when the hospital is overcrowded, and gain time to provide the care needed.
介绍。2019冠状病毒病是本世纪的大流行，造成了不同寻常的情况。随后，医疗和人力资源短缺导致卫生系统崩溃，特别是在第三世界国家。目标。为了支持白军掌握大流行行为，多项研究指出，存在影响COVID-19患者死亡风险的患者相关因素。在本研究中，人工神经网络(ANN)被用于预测COVID-19死亡率。材料和方法。特别是，建模阶段使用了从吉耶勒Mohamed Seddik Ben Yahia医院收集的684个样本的数据库，其中包括患者的既往疾病和血液生物标志物数据。首先，根据文献推荐和专家医疗团队咨询，在输入层选择18个参数。此外，使用人工神经网络对最优输入进行建模，并通过四个性能指标(灵敏度、特异性、精度和准确性)对其性能进行评估。结果。对比研究证明了采用Tansig传递函数训练的(18-12-2)模型的有效性，与文献中提出的其他模型相比，该模型在预测COVID-19死亡率方面表现出更高的性能。随后，利用所提出的优化模型，利用Matlab软件开发了GUI公共界面。结论。最后，在当前的研究中生成了一个可靠且易于使用的图形界面，称为“CoviSurv2021”。后者将非常有助于医务人员选择最紧急的患者优先住院，在医院人满为患时优先考虑患者，并争取时间提供所需的护理。
{"title":"An Artificial Neural Networks model for predicting patients’ mortality due to COVID-19 \"CoviSurv2021\"","authors":"Fatima Haddad, Saliha Ouadah, Lina Lefilef, M. A. Benbouras","doi":"10.30952/ns.11.1.4","DOIUrl":"https://doi.org/10.30952/ns.11.1.4","url":null,"abstract":"Introduction. COVID-19 is the pandemic of the century with the unusual circumstances it generated. Subsequently, there has been medical and human scarcity of resources leading to the health system collapse, especially in third world countries. Objective. To support the white army in grasping the pandemic behavior, several studies have pointed to the existence of patient-related factors affecting COVID-19 patients’ mortality-risk. In the current study, Artificial Neural Network (ANN) has been employed to predict COVID-19 mortality. Material and methods. In particular, the modeling phase was done using a database of 684 samples collected from Mohamed Seddik Ben Yahia Hospital of Jijel, with antecedent diseases and blood biomarkers data of patients. Firstly, 18 parameters were selected in the input layer based on the literature recommendation and expert medical team consultation. Furthermore, the optimal inputs have been modeled using the ANN, and their performance was assessed through four performance measures (sensitivity, specificity, precision, and accuracy). Results. The comparative study proved the effectiveness of (18-12-2) model trained by Tansig transfer function, which displayed a higher performance in predicting COVID-19 mortality, compared to other models proposed in the literature. Afterward, the proposed optimal model was utilized to develop a GUI public interface by Matlab software. Conclusion. Finally, a reliable and easy-to-use graphical interface is generated in the current study dubbed “CoviSurv2021”. This latter will be very helpful for the medical staff to select priority patients who have upper urgency to be hospitalized, prioritize patients when the hospital is overcrowded, and gain time to provide the care needed.","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128457419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In addition to their effect on body composition (fat reduction), conjugated linoleic acid isomers (CLA) can play several health benefits, including anti-cancer, anti-atherogenic, anti-adipogenic, anti-diabetic, anti-inflammatory, possible cholesterolemia regulation, and immune function stimulation. Probiotics have been found to produce CLA, however, there is still controversy in the results obtained on the production and effects of human gut bacterial CLA reported in literature. Most of the biological effects have been attributed to cis9, trans11, and trans10, cis12 isomers. The aim of this review was to highlight and discuss how probiotic bacterial CLA isomers provided health benefits. [Au-delà des effets des isomères conjugués de l’acide linoléique (conjugated linoleic acid isomers (CLA)) sur la composition corporelle (diminution de la graisse), ces composés bioactifs ont des effets sur la santé humaine, tels que les effets anti-can-céreux, anti-athérogéniques, anti-adipogéniques, anti-diabétiques, antiinflammatoires, impact potentiel sur la cholestérolémie et stimulation de la fonction immunitaire. Les bactéries probiotiques ont été trouvées capables de conjuguer l’acide linoléique. Toutefois, peu d’études ont mis le point sur cette production des isomères conjugués d’acide linoléique par des bactéries intestinales humaines et restent peu concluantes. Leurs effets santé ont été reliés à deux types d’isomères, à savoir le 9cis, 11trans et le 10trans, 12cis. La présente mise au point a pour objet de souligner les données disponibles concernant les effets des isomères CLA sur la santé, en particulier ceux produits par des bactéries probiotiques. Les mécanismes impliqués dans leurs activités sont aussi évoqués.]
除了对身体成分(脂肪减少)的影响，共轭亚油酸异构体(CLA)还可以发挥多种健康益处，包括抗癌、抗动脉粥样硬化、抗脂肪生成、抗糖尿病、抗炎、可能的胆固醇血症调节和免疫功能刺激。益生菌已被发现产生CLA，但文献报道的关于人体肠道细菌CLA的产生和作用的结果仍存在争议。大多数生物效应归因于顺式9、反式11和反式10、顺式12异构体。本综述的目的是强调和讨论益生菌CLA异构体如何提供健康益处。[au - delodes效应des isomres共轭亚油酸异构体(共轭亚油酸异构体(CLA))，合成亚油酸异构体，合成亚油酸异构体，合成亚油酸异构体，合成亚油酸异构体，合成亚油酸异构体的生物活性，合成亚油酸异构体，合成亚油酸异构体，合成亚油酸异构体，合成亚油酸异构体，合成亚油酸异构体，合成亚油酸异构体，合成亚油酸异构体。Les bactsamys probiotiques ont samtous trouvsames capables de conjuguer l 'acide linolsamique。然而，在不同的情况下，不同的人会有不同的看法，例如，不同的人会有不同的看法，例如，不同的人会有不同的看法。他们运用健康永久依赖两个类型d 'isomeres,知道勒9 cis, 11 le 10变性,变性等12个cis。该术语指的是化学物质对化学物质的影响，特别是对化学物质对益生菌的影响。[au:] Les msamcanismes impliqusams dans leurs activitsams sonaussi samvoqusams。
{"title":"Conjugated isomers of linoleic acid and health: What about those of bacterial origin ?","authors":"H. Ziar, I. Yahla, A. Riazi","doi":"10.30952/ns.11.1.1","DOIUrl":"https://doi.org/10.30952/ns.11.1.1","url":null,"abstract":"In addition to their effect on body composition (fat reduction), conjugated linoleic acid isomers (CLA) can play several health benefits, including anti-cancer, anti-atherogenic, anti-adipogenic, anti-diabetic, anti-inflammatory, possible cholesterolemia regulation, and immune function stimulation. Probiotics have been found to produce CLA, however, there is still controversy in the results obtained on the production and effects of human gut bacterial CLA reported in literature. Most of the biological effects have been attributed to cis9, trans11, and trans10, cis12 isomers. The aim of this review was to highlight and discuss how probiotic bacterial CLA isomers provided health benefits. [Au-delà des effets des isomères conjugués de l’acide linoléique (conjugated linoleic acid isomers (CLA)) sur la composition corporelle (diminution de la graisse), ces composés bioactifs ont des effets sur la santé humaine, tels que les effets anti-can-céreux, anti-athérogéniques, anti-adipogéniques, anti-diabétiques, antiinflammatoires, impact potentiel sur la cholestérolémie et stimulation de la fonction immunitaire. Les bactéries probiotiques ont été trouvées capables de conjuguer l’acide linoléique. Toutefois, peu d’études ont mis le point sur cette production des isomères conjugués d’acide linoléique par des bactéries intestinales humaines et restent peu concluantes. Leurs effets santé ont été reliés à deux types d’isomères, à savoir le 9cis, 11trans et le 10trans, 12cis. La présente mise au point a pour objet de souligner les données disponibles concernant les effets des isomères CLA sur la santé, en particulier ceux produits par des bactéries probiotiques. Les mécanismes impliqués dans leurs activités sont aussi évoqués.]","PeriodicalId":254787,"journal":{"name":"Nutrition & Santé","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128298430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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