Preparation and Characteristics of Guar Gum-Sodium Alginate Complexed Bone Adhesive Material

Abstract

Comminuted fracture is still a medical problem because of the difficulties for the small bone pieces fixation. Bone adhesive is one of the most potential methods to solve the problem. However, there are a lot of defects in the present medical adhesives. Some adhesives will produce certain poisonous substance in body which would be harmful to people's health. Some have worse adhesive strength and degrade slowly in body. Therefore, it is necessary to search for the new bone adhesive materials for the use in comminuted fracture. A new bone adhesive material, the guar gum- sodium alginate (GS) complexed bone adhesive was developed in the present paper. According to the analysis of IR spectra, XRD patterns and SEM photos, the GS adhesive material had the functional groups of both guar gum and sodium alginate, but its crystal structure was more like that of sodium alginate, and its surface morphology structure was a porous, crosslinking and amorphous surface morphology structure, which could be a good support material for the growth of bone cells.