Polymer biodegradable fixators in the treatment of near- and intra articular fractures

Aleksej M Fajn, A. Vaza, E. Mamatov, E. A. Zhirkova, Sergej F Gneteckij, R. Titov, K. I. Skuratovskaya
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Abstract

We have observed an increase in the number of patients with intra-articular fractures, as well as in the severity of such fractures. Traditionally, metal implants such as wires, capless screws, Herbert screws are used for osteosynthesis of intra-articular fractures with small bone and cartilage fragments. However, the metal implants have their drawbacks. Biodegradable fixatives (BDF) made from a copolymer of polylactic and polyglycolic acids (PLGA) could be an alternative to the implants. Two groups of 132 people with intra-articular fractures of different localization were formed, biodegradable implants were used in the main group, metal implants were used in the control group. The groups were correlated by sex, age and nature of fractures. We compared the time spent in the operating room for similar operations, the number of operations to remove the fixators in both groups, and the number of complications. Compared functional outcomes. We assessed the possibility of interpreting MSCT and MRI data in the isolated use of BDF. In the group with the use of biodegradable implants, fewer removal operations were required (44%) than in the group without the use of biodegradable implants (58%), which is statistically significant. Complications developed in the main group amounted to 3% (4 cases), while in the group with metal implants they amounted to 10% (13 cases). We have found that the use of biodegradable implants has satisfactory clinical results, a low percentage of implant removal operations, and lower complications rate.
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聚合物可生物降解固定物在治疗关节内骨折中的应用
我们观察到关节内骨折患者数量的增加,以及这种骨折的严重程度。传统上,金属植入物如金属丝、无帽螺钉、赫伯特螺钉用于小骨和软骨碎片的关节内骨折的骨融合术。然而,金属植入物也有其缺点。由聚乳酸和聚乙醇酸(PLGA)共聚物制成的可生物降解固定剂(BDF)可以作为植入物的替代品。将132例不同定位的关节内骨折患者分为两组,主组采用生物可降解假体,对照组采用金属假体。这些组是根据性别、年龄和骨折的性质来关联的。我们比较了两组患者在手术室进行类似手术的时间、拆除固定架的手术次数以及并发症的数量。比较功能结果。我们评估了单独使用BDF解释MSCT和MRI数据的可能性。在使用生物可降解种植体的组中,所需的移除手术(44%)少于未使用生物可降解种植体的组(58%),这在统计学上具有显著性。主组并发症发生率为3%(4例),金属种植体组并发症发生率为10%(13例)。我们发现使用生物可降解种植体具有令人满意的临床效果,种植体移除手术比例低,并发症发生率低。
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