Comparative characteristics of the main sanogenetic mechanisms in large laboratory animals (pigs) with acute blood loss and after infusion of an isotonic colloidal solution based on dextran and an isotonic solution based on polyglucin in conditions of general external cooling

Materialy VIII Vserossijskoj konferencii s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka» Pub Date : 2021-12-13 DOI:10.34014/mpphe.2021-231-234

A.O. Shvetc, I. Shperling, A. Krupin, P. A. Romanov, N.N. Matveeva

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Abstract

The experiment was carried out on male pigs, which in the operating room were simulated with acute blood loss (air temperature 23oC). Then the animals were placed in a climatic chamber (minus 50 ° C) for 10 minutes. Then the temperature in the climatic chamber was raised to minus 10 ° C and the introduction of the test solutions to the animals began. It was found that in both groups there were similar indicators of blood pressure. The heart rate and respiratory rate in animals in the group with the experimental solution based on polyglucin derivatives were lower than in the group with the solution based on dextran. Key words: external general cooling, pigs, blood pressure, heart rate, respiratory rate, infusion solution.

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大型实验动物(猪)急性失血和在一般外部冷却条件下输注葡聚糖等渗胶体溶液和多葡聚糖等渗溶液后主要造血机制的比较

实验以雄性猪为实验对象，在手术室模拟急性失血(空气温度23℃)。然后将动物置于气候室(- 50°C) 10分钟。然后将气候室的温度提高到零下10°C，并开始向动物介绍测试溶液。结果发现，两组的血压指标相似。以葡聚糖衍生物为基础的实验溶液组动物心率和呼吸频率均低于以葡聚糖为基础的实验溶液组。关键词:体外综合降温，猪，血压，心率，呼吸率，输液液。

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Materialy VIII Vserossijskoj konferencii s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka»

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