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Materialy VIII Vserossijskoj konferencii s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka»最新文献

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The effect of transcranial magnetic stimulation on the excitability of the motor neuron pools of the muscles of the lower extremities 经颅磁刺激对下肢肌肉运动神经元池兴奋性的影响
S. Ananiev, D. Pavlov, R. Yakupov, V. Golodnova, M. Balykin
The study was conducted on 22 healthy men aged 18-23 years. The primary motor cortex innervating the lower limb was stimulated with transcranial magnetic stimulation. Using transcutaneous electrical stimulation of the spinal cord, evoked motor responses of the muscles of the lower extremities were initiated when electrodes were applied cutaneous between the spinous processes in the Th11-Th12 projection. Research protocol: Determination of the thresholds of BMO of the muscles of the lower extremities during TESCS; determination of the BMO threshold of the TA muscle in TMS; determination of the thresholds of the BMO of the muscles of the lower extremities during TESCS against the background of 80% and 90% TMS. It was found that magnetic stimulation of the motor cortex of the brain leads to an increase in the excitability of the neural structures of the lumbar thickening of the spinal cord and an improvement in neuromuscular interactions. Key words: transcranial magnetic stimulation, transcutaneous electrical stimulation of the spinal cord, neural networks, excitability, neuromuscular interactions.
这项研究对22名年龄在18-23岁的健康男性进行了调查。经颅磁刺激可刺激支配下肢神经的初级运动皮层。使用经皮脊髓电刺激,当电极在Th11-Th12突起之间的皮肤上施加时,引发了下肢肌肉的诱发运动反应。研究方案:TESCS中下肢肌肉BMO阈值的测定;经颅磁刺激法测定TA肌BMO阈值;在80%和90%经颅磁刺激的背景下,测定TESCS期间下肢肌肉BMO的阈值。研究发现,对大脑运动皮层的磁刺激导致腰椎神经结构的兴奋性增加,脊髓增厚,神经肌肉相互作用改善。关键词:经颅磁刺激,经皮脊髓电刺激,神经网络,兴奋性,神经肌肉相互作用
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引用次数: 0
Vascular-tissue relations in the lungs in experimental superinvasive opisthorchiasis 实验性超侵袭性蛇胸病肺血管组织关系
M. Shvedsky, G. S. Solovyov, V. V. Matvienko, V. A. Shidin, O.G. Solovyova, O. F. Istomina
Structural changes in the lungs in superinvasive opisthorchiasis at various stages of invasion were studied. The morphology of permanent epithelial proliferation at the initial stage and their decrease in the late period were revealed. With the formation of granulomas in the interstitial tissue of the respiratory organs, with changes in the chronic period towards the formation of sclerotic foci. Key words: superinvasive opisthorchiasis (CO), metacercariae, acinus, terminal bronchioles (TB), cell infiltrates, pneumocytes.
研究了超侵袭性蛇胸病不同侵袭阶段肺结构的变化。结果表明,永久性上皮细胞增殖初期呈明显的形态变化,后期呈明显的下降趋势。随着呼吸器官间质组织中肉芽肿的形成,随慢性期的变化向硬化灶的形成方向发展。关键词:超侵袭性蛇胸蚴病,囊蚴,腺泡,终末细支气管,细胞浸润,肺细胞。
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引用次数: 0
Microanatomical organization of regional inguinal lymph node parenchyma after endolymphatic injection of gold nanoparticles 内淋巴注射纳米金后腹股沟区域淋巴结实质的显微解剖组织
V. H. Gabitov, A.A. Beisembayev, S. Sulaimankulova, T.E. Kuramaeva, A.N. Saalieva, u.U. Omurbek, M.A. Gabitova
The morphofunctional state of regional lymph nodes of white mongrel rats after endolymphatic introduction of gold nanoparticles with a diameter from 5 nm to 30 nm was studied. Endolymphatic introduction of gold nanoparticles was shown to have a direct immunomodulatory effect even at small sizes of nanogold. Morphological rearrangements in the regional lymph nodes testify to the activation of migration, proliferation and differentiation of immunocompetent cells, which suggests the immunomodulatory effect of gold nanoparticles. Key words: endolymphatic injection of gold nanoparticles, inguinal lymph nodes, cell populations.
研究了内淋巴注入直径为5 ~ 30 nm的金纳米颗粒后,白杂种大鼠局部淋巴结的形态功能状态。内淋巴引入金纳米颗粒被证明具有直接的免疫调节作用,即使是小尺寸的纳米金。局部淋巴结的形态重排证明了免疫活性细胞的迁移、增殖和分化,提示了金纳米颗粒的免疫调节作用。关键词:内淋巴注射纳米金,腹股沟淋巴结,细胞群。
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引用次数: 0
The effect of percutaneous electrical stimulation of the spinal cord on autonomic reactions in the acute period of rehabilitation after ischemic stroke 经皮脊髓电刺激对缺血性脑卒中后急性康复期自主神经反应的影响
Y.Y. Bikbaeva, D. A. Pavlov, A. S. Kuznetsov, E.S. Balykina, I. Antipov
The effect of percutaneous electrical stimulation of the spinal cord on the reactions of the autonomic nervous system in patients after acute cerebral circulatory disorders was evaluated. Patients in the acute period of rehabilitation treatment underwent a course of percutaneous electrical stimulation for 10 days. Before and after rehabilitation, vegetative reactions were assessed using an orthoclinostatic test, an A.M.Wein questionnaire, and neurological disorders on the Scandinavian scale. The inclusion of the course of percutaneous electrical stimulation in the program of physical rehabilitation of patients who have suffered an ischemic stroke indicates an improvement in the motor status of patients and a decrease in the imbalance of sympathetic and parasympathetic influences Keywords: ischemic stroke, percutaneous electrical stimulation of the spinal cord, vegetative reactions
探讨经皮脊髓电刺激对急性脑循环疾病患者自主神经系统反应的影响。患者在康复治疗的急性期进行了一个10天的经皮电刺激疗程。康复前后,植物性反应评估使用直立试验,一个A.M.Wein问卷,以及斯堪的纳维亚量表的神经紊乱。将经皮电刺激纳入缺血性脑卒中患者的身体康复方案,可改善患者的运动状态,减少交感神经和副交感神经的不平衡影响。关键词:缺血性脑卒中,脊髓经皮电刺激,植物性反应
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引用次数: 0
Analysis of the content of nitric oxide (II) metabolites rats of different ages 不同年龄大鼠一氧化氮(II)代谢产物含量分析
Y.I. Belova, O. Yakovleva
Nitrogen monoxide is a gas transmitter that is an important intermediary in many organ systems, especially in the central nervous system. Nitrogen monoxide is involved in the relaxation of smooth vascular muscles, activation of neurons and responsible for the cytotoxicity of macrophages. The study of change nitrogen oxide metabolite concentration helps to determine its effects on human and animal organs. The study was carried out on laboratory animals of different ages. We used a spectrophotometric method to determine the level of metabolites based on the reaction of nitrites to the Griss reagent. We noted that the maximum level of metabolites NO was observed in newborn animals at the age of 4 days. In addition, metabolite concentrations decreased gradually by 14-15 days of life, reaching a minimum of 30 days Key words: nitrogen monoxide, rats, age, metabolites of nitrogen monoxide, spectrophotometry.
一氧化氮是一种气体递质,是许多器官系统,特别是中枢神经系统的重要媒介。一氧化氮参与血管平滑肌的松弛、神经元的激活和巨噬细胞的细胞毒性。研究一氧化氮代谢物浓度的变化有助于确定其对人体和动物器官的影响。这项研究是在不同年龄的实验动物身上进行的。我们采用分光光度法根据亚硝酸盐与Griss试剂的反应来测定代谢物的水平。我们注意到,新生动物的代谢产物NO在4天时达到最高水平。此外,代谢产物浓度在生命的14-15天逐渐下降,在30天达到最低。关键词:一氧化氮,大鼠,年龄,一氧化氮代谢产物,分光光度法。
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引用次数: 0
Analysis of energy expenditure of skiers across the preparatory phase 滑雪者在准备阶段的能量消耗分析
Е.А. Bushmanova
Energy expenditure was calculated at rest and during physical activity by indirect calorimetry using the Oxyson Pro system in 55 highly elite skiers. The results showed that in 75% of athletes, the measured rest energy expenditure were higher than the calculated rest energy expenditure by 20% and was 2139±363 kcal/day. Daily energy expenditure was 5347±907 kcal. In the structure of rest energy expenditure the part of carbohydrates was 67 % and fats was 33%. Generally, energy expenditure was more 5000 kcal. In addition, in our study, it was observed a progressive increase of contribution of carbohydrate oxidation in energy expenditure during high-intensity exercise. Key words: energy expenditure, high-intensity exercise, carbohydrates, fats, skiers, indirect calorimetry.
使用Oxyson Pro系统,通过间接量热法计算了55名高水平滑雪运动员在休息和体育活动期间的能量消耗。结果表明,75%的运动员静息能量消耗测量值比计算值高20%,为2139±363 kcal/d。日能量消耗5347±907 kcal,其余能量消耗结构中碳水化合物占67%,脂肪占33%。一般能量消耗在5000 kcal以上。此外,在我们的研究中,观察到高强度运动中碳水化合物氧化对能量消耗的贡献逐渐增加。关键词:能量消耗,高强度运动,碳水化合物,脂肪,滑雪者,间接量热法
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引用次数: 0
Computer electroacupuncture: rationale for the use in the treatment of painful form of irritable bowel syndrome 计算机电针:用于治疗疼痛性肠易激综合征的基本原理
M.P. Khokhlov, A. B. Peskov, O. Milushkina, S. I. Filippova
In a prospective clinical trial, we have compared the effectiveness of the computerized electroacupuncture (CEAP) added to thestandard pharmacological therapy of the patients with painful form of irritable bowel syndrome (IBS)in the main group against its isolated pharmacological therapy in the control group. The study involved 80 volunteerswhich were previously randomly divided to the 2 equal groups due to the type of treatment. Patients in the main group received three courses of CEAP. Each CEAP course contained the five everyday sessions, the interruption period between courses was one month. The inclusion of CEAP to the complex therapy of the painful IBS was accompanied with decreasingof the pain severity to 42%, byVisual Pain Scale. The patients' subjective condition indicators were significantly improved: the levels of depression (according to the Zung test), actual and personal anxiety (according to the Spiberger-Khanin questionnaire) were decreased, the parameters assessed using the SAN questionnaire were increased. Key words: acupuncture, computer electroacupuncture, irritable bowel syndrome, pain treatment, reflexology.
在一项前瞻性临床试验中,我们比较了计算机电针(CEAP)在标准药物治疗中对主组疼痛性肠易激综合征(IBS)患者的有效性,以及对照组的孤立药物治疗。这项研究涉及80名志愿者,他们之前根据治疗方式被随机分为两组。主组患者接受3个疗程的CEAP治疗。每个CEAP课程包含五个日常课程,课程之间的间隔时间为一个月。根据视觉疼痛量表,将CEAP纳入疼痛性IBS的综合治疗中,疼痛严重程度降低至42%。患者主观状况指标明显改善:抑郁(Zung测验)、实际焦虑和个人焦虑(Spiberger-Khanin问卷)水平下降,SAN问卷评估参数增加。关键词:针灸,电脑电针,肠易激综合征,疼痛治疗,反射疗法。
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引用次数: 0
Quality of life of patients after inguinal hernioplasty by endoscopic methods 内镜下腹股沟疝成形术患者的生活质量
Sh. D. Asutaev, A. N. Poborskiy
A comparative analysis of the indicators of 53 men who underwent inguinal hernioplasty using the TEP (n = 20) and TAPP (n = 33) methods was carried out. Quality of life was assessed using the international questionnaire EQ-5D on the 1st day, 1 month and 12 months after surgery. Monitoring of quality of life parameters showed differences in the assessment of their condition by patients who underwent TEP and TAPP, which were most pronounced on the first day after surgery. The presence of problems during this period for all components of the EQ-5D questionnaire, to a greater extent, was associated by patients with pain / discomfort in the operation area. The latter were maximally manifested in the majority of those who underwent TAPP (64%), which also affected their lower assessment of their health status. The revealed differences disappear within a month after the interventions and are absent 12 months after the operation. Key words: quality of life, inguinal hernioplasty, endoscopic methods.
对53例采用TEP (n = 20)和TAPP (n = 33)方法行腹股沟疝成形术的男性患者的各项指标进行比较分析。术后第1天、1个月和12个月采用国际问卷EQ-5D评估患者的生活质量。对生活质量参数的监测显示,接受TEP和TAPP的患者对其病情的评估存在差异,这种差异在术后第一天最为明显。在此期间,EQ-5D问卷的所有组成部分存在的问题,在很大程度上与患者在手术区域的疼痛/不适有关。后者在大多数接受TAPP的患者(64%)中表现得最为明显,这也影响了他们对健康状况的较低评估。这些差异在干预后1个月内消失,在手术后12个月内消失。关键词:生活质量,腹股沟疝成形术,内镜方法。
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引用次数: 0
Comparative characteristics of the main sanogenetic mechanisms in large laboratory animals (pigs) with acute blood loss and after infusion of an isotonic colloidal solution based on dextran and an isotonic solution based on polyglucin in conditions of general external cooling 大型实验动物(猪)急性失血和在一般外部冷却条件下输注葡聚糖等渗胶体溶液和多葡聚糖等渗溶液后主要造血机制的比较
A.O. Shvetc, I. Shperling, A. Krupin, P. A. Romanov, N.N. Matveeva
The experiment was carried out on male pigs, which in the operating room were simulated with acute blood loss (air temperature 23oC). Then the animals were placed in a climatic chamber (minus 50 ° C) for 10 minutes. Then the temperature in the climatic chamber was raised to minus 10 ° C and the introduction of the test solutions to the animals began. It was found that in both groups there were similar indicators of blood pressure. The heart rate and respiratory rate in animals in the group with the experimental solution based on polyglucin derivatives were lower than in the group with the solution based on dextran. Key words: external general cooling, pigs, blood pressure, heart rate, respiratory rate, infusion solution.
实验以雄性猪为实验对象,在手术室模拟急性失血(空气温度23℃)。然后将动物置于气候室(- 50°C) 10分钟。然后将气候室的温度提高到零下10°C,并开始向动物介绍测试溶液。结果发现,两组的血压指标相似。以葡聚糖衍生物为基础的实验溶液组动物心率和呼吸频率均低于以葡聚糖为基础的实验溶液组。关键词:体外综合降温,猪,血压,心率,呼吸率,输液液。
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引用次数: 0
Some aspects of the treatment of patients with paracolostomy fistulas in outpatient settings 门诊治疗结肠旁造瘘患者的一些方面
E. Birch, A. Smolkina
The analysis of the results of treatment of 15 patients with paracolostomy fistulas treated on an outpatient basis with the use of the sorbent "Celoform" was carried out. The use of modern drugs for the local treatment of wounds at all stages of complex treatment makes it possible to shorten the time of systemic antimicrobial therapy, avoid the development of side effects, and significantly reduce the cost of expensive antibacterial drugs. Key words: colostomy, paracolostomy fistula, sorbent "Coeloform, quality of life.
本文对15例门诊结肠旁造瘘患者使用“Celoform”吸附剂治疗的结果进行了分析。在复杂治疗的各个阶段使用现代药物对伤口进行局部治疗,可以缩短全身抗菌治疗的时间,避免副作用的发展,并显著降低昂贵的抗菌药物的成本。关键词:结肠造口术,结肠旁造瘘,吸附剂腔形,生活质量。
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引用次数: 0
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Materialy VIII Vserossijskoj konferencii s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka»
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